GONCALVES JOANA (Chief Medical Officer) sold 17.3% of their position (7K shares) of ORUKA THERAPEUTICS, INC. on the open market

Open‑market sale worth $462.8K — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 3 sales

GONCALVES JOANA

Filed: 4/15/2026ACC: 0000907654-26-000035

InsiderGONCALVES JOANACIK 1756991

→

IssuerORUKA THERAPEUTICS, INC.CIK 907654

Officer· Chief Medical Officer

Since Feb 2026

-7K

Net shares

Net seller

$462.8K

Total sold

Open market trades

0B · 3S

Total transactions

7K acquired · 14K disposed

Non-Derivative Transactions5

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$6.84

Trade value

$23.94K

% of position

10.5%

4/15/2026

33.38K→36.88K

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$7.80

Trade value

$27.30K

% of position

9.5%

4/15/2026

36.88K→40.38K

Common Stock

Direct

S · Sale

−4.23K

Price / share

$65.73

Trade value

$277.84K

% of position

10.5%

4/15/2026

40.38K→36.15K

Common Stock

Direct

S · Sale

−2.27K

Price / share

$66.56

Trade value

$151.30K

% of position

6.3%

4/15/2026

36.15K→33.88K

Common Stock

Direct

S · Sale

−500.00

Price / share

$67.38

Trade value

$33.69K

% of position

1.5%

4/15/2026

33.88K→33.38K

Total

Net shares

+0.00

Net value

-$411.59K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	4/15/2026	M · Option Exercise	+3.50K	$6.84	$23.94K	10.5%	33.38K	36.88K
Common Stock Direct	4/15/2026	M · Option Exercise	+3.50K	$7.80	$27.30K	9.5%	36.88K	40.38K
Common Stock Direct	4/15/2026	S · Sale	−4.23K	$65.73	$277.84K	10.5%	40.38K	36.15K
Common Stock Direct	4/15/2026	S · Sale	−2.27K	$66.56	$151.30K	6.3%	36.15K	33.88K
Common Stock Direct	4/15/2026	S · Sale	−500.00	$67.38	$33.69K	1.5%	33.88K	33.38K
Total			+0.00		-$411.59K

Derivative Transactions2

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

6.84

Held after

211.06K

Exercisable

—

4/15/2026

Employee Warrant (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

7.80

Held after

182.49K

Exercisable

—

4/15/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee Stock Option (right to buy) Direct	Common Stock3.50K shares	4/15/2026	M · Option Exercise	−3.50K	6.84	—	211.06K
Employee Warrant (right to buy) Direct	Common Stock3.50K shares	4/15/2026	M · Option Exercise	−3.50K	7.80	—	182.49K