Filed: 5/15/2026ACC: 0001892134-26-000002
📋 What this filing means
FRAZIER LIFE SCIENCES MANAGEMENT, L.P. filed this quarterly 13F‑HR report disclosing 38 equity positions with a total reported market value of $3.89B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
38
Positions
$3.89B
Total AUM (reported)
169.23M
Total Shares
Allocation by class
COM$3.07B78.9%
ORDINARY SHARES$542.37M14.0%
COM NEW$140.00M3.6%
ADR$35.78M0.9%
SPONSORED ADR$30.50M0.8%
SHS$24.77M0.6%
ADS$14.62M0.4%
Portfolio Concentration
Top 3$1.65B42.5%
4–10$1.21B31.0%
11–25$858.46M22.1%
Rest$171.99M4.4%
Top 3 weight
42.5%
Top 10 weight
73.5%
Voting Authority Distribution
Total shares with voting rights: 169.23M
Sole
Full voting authority
169.23M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole38
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings38
Rows:
MIRUM PHARMACEUTICALS INC
SOLEShares7.68M
TypeSH
Market value$709.45M
18.25%
Sole
7.68M
Shared
0.00
None
0.00
NEWAMSTERDAM PHARMA COMPANY
SOLEShares16.94M
TypeSH
Market value$542.37M
13.96%
Sole
16.94M
Shared
0.00
None
0.00
ERASCA INC
SOLEShares24.68M
TypeSH
Market value$399.24M
10.27%
Sole
24.68M
Shared
0.00
None
0.00
BRIDGEBIO PHARMA INC
SOLEShares3.45M
TypeSH
Market value$256.06M
6.59%
Sole
3.45M
Shared
0.00
None
0.00
ARCUTIS BIOTHERAPEUTICS INC
SOLEShares9.87M
TypeSH
Market value$232.64M
5.99%
Sole
9.87M
Shared
0.00
None
0.00
MBX BIOSCIENCES INC
SOLEShares6.65M
TypeSH
Market value$198.56M
5.11%
Sole
6.65M
Shared
0.00
None
0.00
PHATHOM PHARMACEUTICALS INC
SOLEShares12.47M
TypeSH
Market value$138.50M
3.56%
Sole
12.47M
Shared
0.00
None
0.00
MAZE THERAPEUTICS INC
SOLEShares4.57M
TypeSH
Market value$136.33M
3.51%
Sole
4.57M
Shared
0.00
None
0.00
KRYSTAL BIOTECH INC
SOLEShares481.31K
TypeSH
Market value$124.33M
3.20%
Sole
481.31K
Shared
0.00
None
0.00
TREVI THERAPEUTICS INC
SOLEShares9.94M
TypeSH
Market value$118.58M
3.05%
Sole
9.94M
Shared
0.00
None
0.00
PALVELLA THERAPEUTICS INC NE
SOLEShares882.40K
TypeSH
Market value$109.99M
2.83%
Sole
882.40K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares4.96M
TypeSH
Market value$99.87M
2.57%
Sole
4.96M
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares1.35M
TypeSH
Market value$86.63M
2.23%
Sole
1.35M
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares1.16M
TypeSH
Market value$76.45M
1.97%
Sole
1.16M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares675.69K
TypeSH
Market value$65.71M
1.69%
Sole
675.69K
Shared
0.00
None
0.00
DYNE THERAPEUTICS INC
SOLEShares3.15M
TypeSH
Market value$57.17M
1.47%
Sole
3.15M
Shared
0.00
None
0.00
SAVARA INC
SOLEShares9.72M
TypeSH
Market value$53.08M
1.37%
Sole
9.72M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares728.64K
TypeSH
Market value$51.11M
1.32%
Sole
728.64K
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares2.54M
TypeSH
Market value$45.38M
1.17%
Sole
2.54M
Shared
0.00
None
0.00
AGIOS PHARMACEUTICALS INC
SOLEShares1.26M
TypeSH
Market value$42.49M
1.09%
Sole
1.26M
Shared
0.00
None
0.00
BIOCRYST PHARMACEUTICALS INC
SOLEShares4.01M
TypeSH
Market value$38.17M
0.98%
Sole
4.01M
Shared
0.00
None
0.00
ZAI LAB LTD
SOLEShares1.90M
TypeSH
Market value$35.78M
0.92%
Sole
1.90M
Shared
0.00
None
0.00
AURA BIOSCIENCES INC
SOLEShares5.10M
TypeSH
Market value$34.12M
0.88%
Sole
5.10M
Shared
0.00
None
0.00
ACADIA PHARMACEUTICALS INC
SOLEShares1.44M
TypeSH
Market value$32.01M
0.82%
Sole
1.44M
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares133.33K
TypeSH
Market value$30.50M
0.78%
Sole
133.33K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
MIRUM PHARMACEUTICALS INCSOLE | COM | 7.68M | SH | $709.45M 18.25% | 7.68M | 0.00 | 0.00 |
NEWAMSTERDAM PHARMA COMPANYSOLE | ORDINARY SHARES | 16.94M | SH | $542.37M 13.96% | 16.94M | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 24.68M | SH | $399.24M 10.27% | 24.68M | 0.00 | 0.00 |
BRIDGEBIO PHARMA INCSOLE | COM | 3.45M | SH | $256.06M 6.59% | 3.45M | 0.00 | 0.00 |
ARCUTIS BIOTHERAPEUTICS INCSOLE | COM | 9.87M | SH | $232.64M 5.99% | 9.87M | 0.00 | 0.00 |
MBX BIOSCIENCES INCSOLE | COM | 6.65M | SH | $198.56M 5.11% | 6.65M | 0.00 | 0.00 |
PHATHOM PHARMACEUTICALS INCSOLE | COM | 12.47M | SH | $138.50M 3.56% | 12.47M | 0.00 | 0.00 |
MAZE THERAPEUTICS INCSOLE | COM | 4.57M | SH | $136.33M 3.51% | 4.57M | 0.00 | 0.00 |
KRYSTAL BIOTECH INCSOLE | COM | 481.31K | SH | $124.33M 3.20% | 481.31K | 0.00 | 0.00 |
TREVI THERAPEUTICS INCSOLE | COM | 9.94M | SH | $118.58M 3.05% | 9.94M | 0.00 | 0.00 |
PALVELLA THERAPEUTICS INC NESOLE | COM | 882.40K | SH | $109.99M 2.83% | 882.40K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 4.96M | SH | $99.87M 2.57% | 4.96M | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 1.35M | SH | $86.63M 2.23% | 1.35M | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 1.16M | SH | $76.45M 1.97% | 1.16M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 675.69K | SH | $65.71M 1.69% | 675.69K | 0.00 | 0.00 |
DYNE THERAPEUTICS INCSOLE | COM | 3.15M | SH | $57.17M 1.47% | 3.15M | 0.00 | 0.00 |
SAVARA INCSOLE | COM | 9.72M | SH | $53.08M 1.37% | 9.72M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 728.64K | SH | $51.11M 1.32% | 728.64K | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM NEW | 2.54M | SH | $45.38M 1.17% | 2.54M | 0.00 | 0.00 |
AGIOS PHARMACEUTICALS INCSOLE | COM | 1.26M | SH | $42.49M 1.09% | 1.26M | 0.00 | 0.00 |
BIOCRYST PHARMACEUTICALS INCSOLE | COM | 4.01M | SH | $38.17M 0.98% | 4.01M | 0.00 | 0.00 |
ZAI LAB LTDSOLE | ADR | 1.90M | SH | $35.78M 0.92% | 1.90M | 0.00 | 0.00 |
AURA BIOSCIENCES INCSOLE | COM | 5.10M | SH | $34.12M 0.88% | 5.10M | 0.00 | 0.00 |
ACADIA PHARMACEUTICALS INCSOLE | COM | 1.44M | SH | $32.01M 0.82% | 1.44M | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 133.33K | SH | $30.50M 0.78% | 133.33K | 0.00 | 0.00 |
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