Filed: 2/13/2026ACC: 0001892134-26-000001
📋 What this filing means
FRAZIER LIFE SCIENCES MANAGEMENT, L.P. filed this quarterly 13F‑HR report disclosing 40 equity positions with a total reported market value of $3.72B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
40
Positions
$3.72B
Total AUM (reported)
163.70M
Total Shares
Allocation by class
COM$2.79B74.9%
ORDINARY SHARES$594.39M16.0%
COM NEW$153.69M4.1%
SPONSORED ADS$71.23M1.9%
ADR$33.56M0.9%
SPONSORED ADR$28.43M0.8%
SHS$19.60M0.5%
Portfolio Concentration
Top 3$1.42B38.1%
4–10$1.23B32.9%
11–25$847.48M22.8%
Rest$231.81M6.2%
Top 3 weight
38.1%
Top 10 weight
71.0%
Voting Authority Distribution
Total shares with voting rights: 163.70M
Sole
Full voting authority
163.70M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole40
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings40
Rows:
NEWAMSTERDAM PHARMA COMPANY
SOLEShares16.94M
TypeSH
Market value$594.39M
15.96%
Sole
16.94M
Shared
0.00
None
0.00
MIRUM PHARMACEUTICALS INC
SOLEShares6.80M
TypeSH
Market value$536.75M
14.42%
Sole
6.80M
Shared
0.00
None
0.00
ARCUTIS BIOTHERAPEUTICS INC
SOLEShares9.87M
TypeSH
Market value$286.76M
7.70%
Sole
9.87M
Shared
0.00
None
0.00
BRIDGEBIO PHARMA INC
SOLEShares3.55M
TypeSH
Market value$271.20M
7.28%
Sole
3.55M
Shared
0.00
None
0.00
MBX BIOSCIENCES INC
SOLEShares6.65M
TypeSH
Market value$209.80M
5.64%
Sole
6.65M
Shared
0.00
None
0.00
PHATHOM PHARMACEUTICALS INC
SOLEShares12.47M
TypeSH
Market value$206.82M
5.55%
Sole
12.47M
Shared
0.00
None
0.00
MAZE THERAPEUTICS INC
SOLEShares4.57M
TypeSH
Market value$189.22M
5.08%
Sole
4.57M
Shared
0.00
None
0.00
TREVI THERAPEUTICS INC
SOLEShares10.26M
TypeSH
Market value$128.45M
3.45%
Sole
10.26M
Shared
0.00
None
0.00
KRYSTAL BIOTECH INC
SOLEShares488.46K
TypeSH
Market value$120.42M
3.23%
Sole
488.46K
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares1.26M
TypeSH
Market value$100.06M
2.69%
Sole
1.26M
Shared
0.00
None
0.00
ERASCA INC
SOLEShares22.73M
TypeSH
Market value$84.55M
2.27%
Sole
22.73M
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares5.04M
TypeSH
Market value$81.39M
2.19%
Sole
5.04M
Shared
0.00
None
0.00
PALVELLA THERAPEUTICS INC NE
SOLEShares722.40K
TypeSH
Market value$75.61M
2.03%
Sole
722.40K
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares983.13K
TypeSH
Market value$70.91M
1.90%
Sole
983.13K
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares797.46K
TypeSH
Market value$63.52M
1.71%
Sole
797.46K
Shared
0.00
None
0.00
DYNE THERAPEUTICS INC
SOLEShares3.15M
TypeSH
Market value$61.67M
1.66%
Sole
3.15M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares728.64K
TypeSH
Market value$59.66M
1.60%
Sole
728.64K
Shared
0.00
None
0.00
SAVARA INC
SOLEShares9.86M
TypeSH
Market value$59.47M
1.60%
Sole
9.86M
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares934.64K
TypeSH
Market value$59.39M
1.60%
Sole
934.64K
Shared
0.00
None
0.00
ABIVAX SA
SOLEShares378.30K
TypeSH
Market value$51.02M
1.37%
Sole
378.30K
Shared
0.00
None
0.00
LEXEO THERAPEUTICS INC
SOLEShares4.42M
TypeSH
Market value$43.94M
1.18%
Sole
4.42M
Shared
0.00
None
0.00
AGIOS PHARMACEUTICALS INC
SOLEShares1.28M
TypeSH
Market value$34.83M
0.94%
Sole
1.28M
Shared
0.00
None
0.00
ACADIA PHARMACEUTICALS INC
SOLEShares1.30M
TypeSH
Market value$34.65M
0.93%
Sole
1.30M
Shared
0.00
None
0.00
ZAI LAB LTD
SOLEShares1.90M
TypeSH
Market value$33.56M
0.90%
Sole
1.90M
Shared
0.00
None
0.00
RAPT THERAPEUTICS INC
SOLEShares983.33K
TypeSH
Market value$33.31M
0.89%
Sole
983.33K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
NEWAMSTERDAM PHARMA COMPANYSOLE | ORDINARY SHARES | 16.94M | SH | $594.39M 15.96% | 16.94M | 0.00 | 0.00 |
MIRUM PHARMACEUTICALS INCSOLE | COM | 6.80M | SH | $536.75M 14.42% | 6.80M | 0.00 | 0.00 |
ARCUTIS BIOTHERAPEUTICS INCSOLE | COM | 9.87M | SH | $286.76M 7.70% | 9.87M | 0.00 | 0.00 |
BRIDGEBIO PHARMA INCSOLE | COM | 3.55M | SH | $271.20M 7.28% | 3.55M | 0.00 | 0.00 |
MBX BIOSCIENCES INCSOLE | COM | 6.65M | SH | $209.80M 5.64% | 6.65M | 0.00 | 0.00 |
PHATHOM PHARMACEUTICALS INCSOLE | COM | 12.47M | SH | $206.82M 5.55% | 12.47M | 0.00 | 0.00 |
MAZE THERAPEUTICS INCSOLE | COM | 4.57M | SH | $189.22M 5.08% | 4.57M | 0.00 | 0.00 |
TREVI THERAPEUTICS INCSOLE | COM | 10.26M | SH | $128.45M 3.45% | 10.26M | 0.00 | 0.00 |
KRYSTAL BIOTECH INCSOLE | COM | 488.46K | SH | $120.42M 3.23% | 488.46K | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 1.26M | SH | $100.06M 2.69% | 1.26M | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 22.73M | SH | $84.55M 2.27% | 22.73M | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 5.04M | SH | $81.39M 2.19% | 5.04M | 0.00 | 0.00 |
PALVELLA THERAPEUTICS INC NESOLE | COM | 722.40K | SH | $75.61M 2.03% | 722.40K | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 983.13K | SH | $70.91M 1.90% | 983.13K | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 797.46K | SH | $63.52M 1.71% | 797.46K | 0.00 | 0.00 |
DYNE THERAPEUTICS INCSOLE | COM | 3.15M | SH | $61.67M 1.66% | 3.15M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 728.64K | SH | $59.66M 1.60% | 728.64K | 0.00 | 0.00 |
SAVARA INCSOLE | COM | 9.86M | SH | $59.47M 1.60% | 9.86M | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 934.64K | SH | $59.39M 1.60% | 934.64K | 0.00 | 0.00 |
ABIVAX SASOLE | SPONSORED ADS | 378.30K | SH | $51.02M 1.37% | 378.30K | 0.00 | 0.00 |
LEXEO THERAPEUTICS INCSOLE | COM | 4.42M | SH | $43.94M 1.18% | 4.42M | 0.00 | 0.00 |
AGIOS PHARMACEUTICALS INCSOLE | COM | 1.28M | SH | $34.83M 0.94% | 1.28M | 0.00 | 0.00 |
ACADIA PHARMACEUTICALS INCSOLE | COM | 1.30M | SH | $34.65M 0.93% | 1.30M | 0.00 | 0.00 |
ZAI LAB LTDSOLE | ADR | 1.90M | SH | $33.56M 0.90% | 1.90M | 0.00 | 0.00 |
RAPT THERAPEUTICS INCSOLE | COM NEW | 983.33K | SH | $33.31M 0.89% | 983.33K | 0.00 | 0.00 |
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