Filed: 2/14/2024ACC: 0001892134-24-000002
📋 What this filing means
FRAZIER LIFE SCIENCES MANAGEMENT, L.P. filed this quarterly 13F‑HR report disclosing 49 equity positions with a total reported market value of $1.87B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
49
Positions
$1.87B
Total AUM (reported)
114.46M
Total Shares
Allocation by class
COM$1.62B86.7%
ORDINARY SHARES$135.51M7.2%
SPONSORED ADS$72.85M3.9%
SPON ADS$24.13M1.3%
ADS$15.31M0.8%
*W EXP 11/22/202$1.57M0.1%
Portfolio Concentration
Top 3$484.25M25.9%
4–10$626.71M33.5%
11–25$479.35M25.6%
Rest$280.04M15.0%
Top 3 weight
25.9%
Top 10 weight
59.4%
Voting Authority Distribution
Total shares with voting rights: 114.46M
Sole
Full voting authority
114.46M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole49
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings49
Rows:
MIRUM PHARMACEUTICALS INC
SOLEShares6.50M
TypeSH
Market value$191.74M
10.25%
Sole
6.50M
Shared
0.00
None
0.00
HILLEVAX INC
SOLEShares9.78M
TypeSH
Market value$156.99M
8.39%
Sole
9.78M
Shared
0.00
None
0.00
NEWAMSTERDAM PHARMA COMPANY
SOLEShares12.13M
TypeSH
Market value$135.51M
7.25%
Sole
12.13M
Shared
0.00
None
0.00
KRYSTAL BIOTECH INC
SOLEShares988.46K
TypeSH
Market value$122.63M
6.56%
Sole
988.46K
Shared
0.00
None
0.00
BRIDGEBIO PHARMA INC
SOLEShares2.73M
TypeSH
Market value$110.05M
5.88%
Sole
2.73M
Shared
0.00
None
0.00
RHYTHM PHARMACEUTICALS INC
SOLEShares2.37M
TypeSH
Market value$109.01M
5.83%
Sole
2.37M
Shared
0.00
None
0.00
PHATHOM PHARMACEUTICALS INC
SOLEShares10.11M
TypeSH
Market value$92.30M
4.93%
Sole
10.11M
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares1.16M
TypeSH
Market value$73.12M
3.91%
Sole
1.16M
Shared
0.00
None
0.00
VERONA PHARMA PLC
SOLEShares3.01M
TypeSH
Market value$59.93M
3.20%
Sole
3.01M
Shared
0.00
None
0.00
ALPINE IMMUNE SCIENCES INC
SOLEShares3.13M
TypeSH
Market value$59.68M
3.19%
Sole
3.13M
Shared
0.00
None
0.00
APELLIS PHARMACEUTICALS INC
SOLEShares885.16K
TypeSH
Market value$52.99M
2.83%
Sole
885.16K
Shared
0.00
None
0.00
ROCKET PHARMACEUTICALS INC
SOLEShares1.52M
TypeSH
Market value$45.64M
2.44%
Sole
1.52M
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares785K
TypeSH
Market value$45.34M
2.42%
Sole
785K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares3.62M
TypeSH
Market value$44.37M
2.37%
Sole
3.62M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares1.79M
TypeSH
Market value$36.20M
1.94%
Sole
1.79M
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares2.67M
TypeSH
Market value$29.18M
1.56%
Sole
2.67M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares997.46K
TypeSH
Market value$28.61M
1.53%
Sole
997.46K
Shared
0.00
None
0.00
AN2 THERAPEUTICS INC
SOLEShares1.39M
TypeSH
Market value$28.46M
1.52%
Sole
1.39M
Shared
0.00
None
0.00
ARCUTIS BIOTHERAPEUTICS INC
SOLEShares8.76M
TypeSH
Market value$28.31M
1.51%
Sole
8.76M
Shared
0.00
None
0.00
AEROVATE THERAPEUTICS INC
SOLEShares1.20M
TypeSH
Market value$27.27M
1.46%
Sole
1.20M
Shared
0.00
None
0.00
AUTOLUS THERAPEUTICS PLC
SOLEShares3.75M
TypeSH
Market value$24.13M
1.29%
Sole
3.75M
Shared
0.00
None
0.00
MACROGENICS INC
SOLEShares2.40M
TypeSH
Market value$23.10M
1.24%
Sole
2.40M
Shared
0.00
None
0.00
ACADIA PHARMACEUTICALS INC
SOLEShares730.92K
TypeSH
Market value$22.89M
1.22%
Sole
730.92K
Shared
0.00
None
0.00
89BIO INC
SOLEShares2M
TypeSH
Market value$22.34M
1.19%
Sole
2M
Shared
0.00
None
0.00
MERUS N V
SOLEShares746.48K
TypeSH
Market value$20.53M
1.10%
Sole
746.48K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
MIRUM PHARMACEUTICALS INCSOLE | COM | 6.50M | SH | $191.74M 10.25% | 6.50M | 0.00 | 0.00 |
HILLEVAX INCSOLE | COM | 9.78M | SH | $156.99M 8.39% | 9.78M | 0.00 | 0.00 |
NEWAMSTERDAM PHARMA COMPANYSOLE | ORDINARY SHARES | 12.13M | SH | $135.51M 7.25% | 12.13M | 0.00 | 0.00 |
KRYSTAL BIOTECH INCSOLE | COM | 988.46K | SH | $122.63M 6.56% | 988.46K | 0.00 | 0.00 |
BRIDGEBIO PHARMA INCSOLE | COM | 2.73M | SH | $110.05M 5.88% | 2.73M | 0.00 | 0.00 |
RHYTHM PHARMACEUTICALS INCSOLE | COM | 2.37M | SH | $109.01M 5.83% | 2.37M | 0.00 | 0.00 |
PHATHOM PHARMACEUTICALS INCSOLE | COM | 10.11M | SH | $92.30M 4.93% | 10.11M | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 1.16M | SH | $73.12M 3.91% | 1.16M | 0.00 | 0.00 |
VERONA PHARMA PLCSOLE | SPONSORED ADS | 3.01M | SH | $59.93M 3.20% | 3.01M | 0.00 | 0.00 |
ALPINE IMMUNE SCIENCES INCSOLE | COM | 3.13M | SH | $59.68M 3.19% | 3.13M | 0.00 | 0.00 |
APELLIS PHARMACEUTICALS INCSOLE | COM | 885.16K | SH | $52.99M 2.83% | 885.16K | 0.00 | 0.00 |
ROCKET PHARMACEUTICALS INCSOLE | COM | 1.52M | SH | $45.64M 2.44% | 1.52M | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 785K | SH | $45.34M 2.42% | 785K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 3.62M | SH | $44.37M 2.37% | 3.62M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 1.79M | SH | $36.20M 1.94% | 1.79M | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 2.67M | SH | $29.18M 1.56% | 2.67M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 997.46K | SH | $28.61M 1.53% | 997.46K | 0.00 | 0.00 |
AN2 THERAPEUTICS INCSOLE | COM | 1.39M | SH | $28.46M 1.52% | 1.39M | 0.00 | 0.00 |
ARCUTIS BIOTHERAPEUTICS INCSOLE | COM | 8.76M | SH | $28.31M 1.51% | 8.76M | 0.00 | 0.00 |
AEROVATE THERAPEUTICS INCSOLE | COM | 1.20M | SH | $27.27M 1.46% | 1.20M | 0.00 | 0.00 |
AUTOLUS THERAPEUTICS PLCSOLE | SPON ADS | 3.75M | SH | $24.13M 1.29% | 3.75M | 0.00 | 0.00 |
MACROGENICS INCSOLE | COM | 2.40M | SH | $23.10M 1.24% | 2.40M | 0.00 | 0.00 |
ACADIA PHARMACEUTICALS INCSOLE | COM | 730.92K | SH | $22.89M 1.22% | 730.92K | 0.00 | 0.00 |
89BIO INCSOLE | COM | 2M | SH | $22.34M 1.19% | 2M | 0.00 | 0.00 |
MERUS N VSOLE | COM | 746.48K | SH | $20.53M 1.10% | 746.48K | 0.00 | 0.00 |
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