FRANCIS CHRIS (See Remarks) sold 94.6% of their position (441.03K shares) of WAVE LIFE SCIENCES LTD. on the open market

Open‑market sale worth $6.43M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 9 sales

FRANCIS CHRIS

Filed: 12/10/2025ACC: 0001193125-25-314737

InsiderFRANCIS CHRISCIK 1657709

→

IssuerWAVE LIFE SCIENCES LTD.CIK 1631574

Officer· See Remarks

Since Jul 2018

-441.03K

Net shares

Net seller

$6.43M

Total sold

Open market trades

0B · 9S

Total transactions

441.03K acquired · 882.06K disposed

Non-Derivative Transactions18

Ordinary Shares

Direct

M · Option Exercise

+28.13K

Price / share

$3.14

Trade value

$88.31K

% of position

112.5%

12/8/2025

25K→53.13K

Ordinary Shares

Direct

S · Sale

−28.13K

Price / share

$14.50

Trade value

$407.81K

% of position

52.9%

12/8/2025

53.13K→25K

Ordinary Shares

Direct

M · Option Exercise

+107.40K

Price / share

$3.87

Trade value

$415.64K

% of position

429.6%

12/8/2025

25K→132.40K

Ordinary Shares

Direct

S · Sale

−107.40K

Price / share

$14.56

Trade value

$1.56M

% of position

81.1%

12/8/2025

132.40K→25K

Ordinary Shares

Direct

M · Option Exercise

+45.88K

Price / share

$4.75

Trade value

$217.94K

% of position

183.5%

12/8/2025

25K→70.88K

Ordinary Shares

Direct

S · Sale

−45.88K

Price / share

$14.50

Trade value

$665.29K

% of position

64.7%

12/8/2025

70.88K→25K

Ordinary Shares

Direct

M · Option Exercise

+9.38K

Price / share

$3.14

Trade value

$29.44K

% of position

37.5%

12/8/2025

25K→34.38K

Ordinary Shares

Direct

S · Sale

−9.38K

Price / share

$15.00

Trade value

$140.63K

% of position

27.3%

12/8/2025

34.38K→25K

Ordinary Shares

Direct

M · Option Exercise

+37.50K

Price / share

$3.14

Trade value

$117.75K

% of position

150.0%

12/8/2025

25K→62.50K

Ordinary Shares

Direct

S · Sale

−37.50K

Price / share

$14.08

Trade value

$528K

% of position

60.0%

12/8/2025

62.50K→25K

Ordinary Shares

Direct

M · Option Exercise

+17.90K

Price / share

$3.87

Trade value

$69.27K

% of position

71.6%

12/8/2025

25K→42.90K

Ordinary Shares

Direct

S · Sale

−17.90K

Price / share

$15.00

Trade value

$268.50K

% of position

41.7%

12/8/2025

42.90K→25K

Ordinary Shares

Direct

M · Option Exercise

+122.35K

Price / share

$4.75

Trade value

$581.16K

% of position

489.4%

12/8/2025

25K→147.35K

Ordinary Shares

Direct

S · Sale

−122.35K

Price / share

$14.20

Trade value

$1.74M

% of position

83.0%

12/8/2025

147.35K→25K

Ordinary Shares

Direct

M · Option Exercise

+50K

Price / share

$10.48

Trade value

$524K

% of position

200.0%

12/8/2025

25K→75K

Ordinary Shares

Direct

S · Sale

−50K

Price / share

$16.00

Trade value

$800K

% of position

66.7%

12/8/2025

75K→25K

Ordinary Shares

Direct

M · Option Exercise

+22.50K

Price / share

$2.83

Trade value

$63.67K

% of position

90.0%

12/8/2025

25K→47.50K

Ordinary Shares

Direct

S · Sale

−22.50K

Price / share

$14.08

Trade value

$316.80K

% of position

47.4%

12/8/2025

47.50K→25K

Total

Net shares

+0.00

Net value

-$4.32M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+28.13K	$3.14	$88.31K	112.5%	25K	53.13K
Ordinary Shares Direct	12/8/2025	S · Sale	−28.13K	$14.50	$407.81K	52.9%	53.13K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+107.40K	$3.87	$415.64K	429.6%	25K	132.40K
Ordinary Shares Direct	12/8/2025	S · Sale	−107.40K	$14.56	$1.56M	81.1%	132.40K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+45.88K	$4.75	$217.94K	183.5%	25K	70.88K
Ordinary Shares Direct	12/8/2025	S · Sale	−45.88K	$14.50	$665.29K	64.7%	70.88K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+9.38K	$3.14	$29.44K	37.5%	25K	34.38K
Ordinary Shares Direct	12/8/2025	S · Sale	−9.38K	$15.00	$140.63K	27.3%	34.38K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+37.50K	$3.14	$117.75K	150.0%	25K	62.50K
Ordinary Shares Direct	12/8/2025	S · Sale	−37.50K	$14.08	$528K	60.0%	62.50K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+17.90K	$3.87	$69.27K	71.6%	25K	42.90K
Ordinary Shares Direct	12/8/2025	S · Sale	−17.90K	$15.00	$268.50K	41.7%	42.90K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+122.35K	$4.75	$581.16K	489.4%	25K	147.35K
Ordinary Shares Direct	12/8/2025	S · Sale	−122.35K	$14.20	$1.74M	83.0%	147.35K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+50K	$10.48	$524K	200.0%	25K	75K
Ordinary Shares Direct	12/8/2025	S · Sale	−50K	$16.00	$800K	66.7%	75K	25K
Ordinary Shares Direct	12/8/2025	M · Option Exercise	+22.50K	$2.83	$63.67K	90.0%	25K	47.50K
Ordinary Shares Direct	12/8/2025	S · Sale	−22.50K	$14.08	$316.80K	47.4%	47.50K	25K
Total			+0.00		-$4.32M

Derivative Transactions5

Share Option (right to buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

75K shares

−75K

Strike price

3.14

Held after

9.38K

Exercisable

—

12/8/2025

Share Option (right to buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

125.30K shares

−125.30K

Strike price

3.87

Held after

161.10K

Exercisable

—

12/8/2025

Share Option (right to buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

168.23K shares

−168.23K

Strike price

4.75

Held after

76.47K

Exercisable

—

12/8/2025

Share Option (right to buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

50K shares

−50K

Strike price

10.48

Held after

0.00

Exercisable

—

12/8/2025

Share Option (right to buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

22.50K shares

−22.50K

Strike price

2.83

Held after

0.00

Exercisable

—

12/8/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Share Option (right to buy) Direct	Ordinary Shares75K shares	12/8/2025	M · Option Exercise	−75K	3.14	—	9.38K
Share Option (right to buy) Direct	Ordinary Shares125.30K shares	12/8/2025	M · Option Exercise	−125.30K	3.87	—	161.10K
Share Option (right to buy) Direct	Ordinary Shares168.23K shares	12/8/2025	M · Option Exercise	−168.23K	4.75	—	76.47K
Share Option (right to buy) Direct	Ordinary Shares50K shares	12/8/2025	M · Option Exercise	−50K	10.48	—	0.00
Share Option (right to buy) Direct	Ordinary Shares22.50K shares	12/8/2025	M · Option Exercise	−22.50K	2.83	—	0.00