FMR LLC

PrivateCIK: 315066

Location

BOSTON, MA

FMR LLC

Filed: 12/10/2025ACC: 0001193125-25-313977

InsiderFMR LLCCIK 315066

→

IssuerSTRUCTURE THERAPEUTICS INC.CIK 1888886

10% OwnerOther

Since Feb 2023

-52.36K

Net shares

Net seller

$0.00

Total acquired

0

Open market trades

0B · 0S

10

Total transactions

52.36K disposed

Non-Derivative Transactions0

No non-derivative transactions reported

Derivative Transactions10

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

2.13K shares

Shares

−709.00

Strike price

Held after

3.39K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

549.00 shares

Shares

−183.00

Strike price

Held after

3.21K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

1.43K shares

Shares

−475.00

Strike price

Held after

2.73K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

4.24K shares

Shares

−1.41K

Strike price

Held after

1.32K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

3.96K shares

Shares

−1.32K

Strike price

Held after

1.00

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

25.01K shares

Shares

−8.34K

Strike price

Held after

39.92K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

6.48K shares

Shares

−2.16K

Strike price

Held after

37.76K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

16.77K shares

Shares

−5.59K

Strike price

Held after

32.17K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

49.91K shares

Shares

−16.64K

Strike price

Held after

15.54K

Exercisable

—

12/8/2025

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

46.60K shares

Shares

−15.54K

Strike price

Held after

0.00

Exercisable

—

12/8/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
American Depositary Shares Indirect	Ordinary Shares2.13K shares	12/8/2025	S · Sale	−709.00		—	3.39K
American Depositary Shares Indirect	Ordinary Shares549.00 shares	12/8/2025	S · Sale	−183.00		—	3.21K
American Depositary Shares Indirect	Ordinary Shares1.43K shares	12/8/2025	S · Sale	−475.00		—	2.73K
American Depositary Shares Indirect	Ordinary Shares4.24K shares	12/8/2025	S · Sale	−1.41K		—	1.32K
American Depositary Shares Indirect	Ordinary Shares3.96K shares	12/8/2025	S · Sale	−1.32K		—	1.00
American Depositary Shares Indirect	Ordinary Shares25.01K shares	12/8/2025	S · Sale	−8.34K		—	39.92K
American Depositary Shares Indirect	Ordinary Shares6.48K shares	12/8/2025	S · Sale	−2.16K		—	37.76K
American Depositary Shares Indirect	Ordinary Shares16.77K shares	12/8/2025	S · Sale	−5.59K		—	32.17K
American Depositary Shares Indirect	Ordinary Shares49.91K shares	12/8/2025	S · Sale	−16.64K		—	15.54K
American Depositary Shares Indirect	Ordinary Shares46.60K shares	12/8/2025	S · Sale	−15.54K		—	0.00

Non-Derivative Holdings (Post-Transaction)2

Ordinary Shares

Indirect

Shares owned36.91K

Ordinary Shares

Indirect

Shares owned434.30K

Total

471.21K indirect471.21K

Security Title	Shares Owned	Ownership Type
Ordinary Shares	36.91K	Indirect
Ordinary Shares	434.30K	Indirect
Total	471.21K	471.21K indirect

Derivative Holdings (Post-Transaction)1

American Depositary Shares

Indirect

Underlying security

Ordinary Shares

Underlying shares

4.55M

Shares owned

1.52M

Exercise price

Expiration

—

Exercise window

—

Total

Underlying

4.55M

Owned

1.52M

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
American Depositary Shares Indirect	Ordinary Shares		—	—	4.55M	1.52M
Total					4.55M	1.52M

FMR LLC — Insider Transaction (Form 4) Filed Dec 10, 2025 | Finecho