FLANAGAN W. MICHAEL (Chief Technical Officer) reported 1 transaction at AVIDITY BIOSCIENCES, INC.

Review the transaction codes below to understand the nature of each event.

FLANAGAN W. MICHAEL

Filed: 2/27/2026ACC: 0001193125-26-082261

InsiderFLANAGAN W. MICHAELCIK 1841990

→

IssuerAVIDITY BIOSCIENCES, INC.CIK 1599901

Officer· Chief Technical Officer

Since Jan 2021

-547.87K

Net shares

Net seller

$0.00

Total acquired

Open market trades

0B · 0S

Total transactions

547.87K disposed

Non-Derivative Transactions1

Common Stock

Direct

D · Disposition

−150.37K

Price / share

—

Trade value

—

% of position

New position

2/27/2026

150.37K→0.00

Total

Net shares

−150.37K

Net value

$0.00

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	2/27/2026	D · Disposition	−150.37K	—	—	New position	150.37K	0.00
Total			−150.37K		$0.00

Derivative Transactions6

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

25K shares

−25K

Strike price

26.75

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

66.50K shares

−66.50K

Strike price

14.22

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

96K shares

−96K

Strike price

22.47

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

72K shares

−72K

Strike price

6.57

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

88K shares

−88K

Strike price

10.16

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

50K shares

−50K

Strike price

31.42

Held after

0.00

Exercisable

—

2/27/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable
Stock Option (Right to Buy) Direct	Common Stock25K shares	2/27/2026	D · Disposition	−25K	26.75	—
Stock Option (Right to Buy) Direct	Common Stock66.50K shares	2/27/2026	D · Disposition	−66.50K	14.22	—
Stock Option (Right to Buy) Direct	Common Stock96K shares	2/27/2026	D · Disposition	−96K	22.47	—
Stock Option (Right to Buy) Direct	Common Stock72K shares	2/27/2026	D · Disposition	−72K	6.57	—
Stock Option (Right to Buy) Direct	Common Stock88K shares	2/27/2026	D · Disposition	−88K	10.16	—
Stock Option (Right to Buy) Direct	Common Stock50K shares	2/27/2026	D · Disposition	−50K	31.42	—