DETHEUX MICHEL (Chief Executive Officer) sold 156.85K shares of ITEOS THERAPEUTICS, INC. on the open market

Open‑market sale worth $1.59M. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 6 sales

DETHEUX MICHEL

Filed: 6/6/2025ACC: 0000950170-25-083411

InsiderDETHEUX MICHELCIK 1816196

→

IssuerITEOS THERAPEUTICS, INC.CIK 1808865

DirectorOfficer· Chief Executive Officer

Since Jul 2020

-156.85K

Net shares

Net seller

$1.59M

Total sold

Open market trades

0B · 6S

Total transactions

156.85K acquired · 313.69K disposed

Non-Derivative Transactions12

Common Stock

Direct

M · Option Exercise

+8.40K

Price / share

$4.30

Trade value

$36.12K

% of position

6.2%

6/4/2025

135.90K→144.30K

Common Stock

Direct

S · Sale

−8.40K

Price / share

$10.10

Trade value

$84.84K

% of position

5.8%

6/4/2025

144.30K→135.90K

Common Stock

Indirect

M · Option Exercise

+43.88K

Price / share

$4.30

Trade value

$188.70K

% of position

New position

6/4/2025

0.00→43.88K

Common Stock

Indirect

S · Sale

−43.88K

Price / share

$10.10

Trade value

$443.22K

% of position

New position

6/4/2025

43.88K→0.00

Common Stock

Direct

M · Option Exercise

+8.40K

Price / share

$4.30

Trade value

$36.12K

% of position

6.2%

6/5/2025

135.90K→144.30K

Common Stock

Direct

S · Sale

−8.40K

Price / share

$10.15

Trade value

$85.26K

% of position

5.8%

6/5/2025

144.30K→135.90K

Common Stock

Indirect

M · Option Exercise

+43.88K

Price / share

$4.30

Trade value

$188.69K

% of position

New position

6/5/2025

0.00→43.88K

Common Stock

Indirect

S · Sale

−43.88K

Price / share

$10.15

Trade value

$445.40K

% of position

New position

6/5/2025

43.88K→0.00

Common Stock

Direct

M · Option Exercise

+8.40K

Price / share

$4.30

Trade value

$36.12K

% of position

6.2%

6/6/2025

135.90K→144.30K

Common Stock

Direct

S · Sale

−8.40K

Price / share

$10.21

Trade value

$85.76K

% of position

5.8%

6/6/2025

144.30K→135.90K

Common Stock

Indirect

M · Option Exercise

+43.88K

Price / share

$4.30

Trade value

$188.69K

% of position

New position

6/6/2025

0.00→43.88K

Common Stock

Indirect

S · Sale

−43.88K

Price / share

$10.21

Trade value

$448.04K

% of position

New position

6/6/2025

43.88K→0.00

Total

Net shares

+0.00

Net value

-$918.08K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	6/4/2025	M · Option Exercise	+8.40K	$4.30	$36.12K	6.2%	135.90K	144.30K
Common Stock Direct	6/4/2025	S · Sale	−8.40K	$10.10	$84.84K	5.8%	144.30K	135.90K
Common Stock Indirect	6/4/2025	M · Option Exercise	+43.88K	$4.30	$188.70K	New position	0.00	43.88K
Common Stock Indirect	6/4/2025	S · Sale	−43.88K	$10.10	$443.22K	New position	43.88K	0.00
Common Stock Direct	6/5/2025	M · Option Exercise	+8.40K	$4.30	$36.12K	6.2%	135.90K	144.30K
Common Stock Direct	6/5/2025	S · Sale	−8.40K	$10.15	$85.26K	5.8%	144.30K	135.90K
Common Stock Indirect	6/5/2025	M · Option Exercise	+43.88K	$4.30	$188.69K	New position	0.00	43.88K
Common Stock Indirect	6/5/2025	S · Sale	−43.88K	$10.15	$445.40K	New position	43.88K	0.00
Common Stock Direct	6/6/2025	M · Option Exercise	+8.40K	$4.30	$36.12K	6.2%	135.90K	144.30K
Common Stock Direct	6/6/2025	S · Sale	−8.40K	$10.21	$85.76K	5.8%	144.30K	135.90K
Common Stock Indirect	6/6/2025	M · Option Exercise	+43.88K	$4.30	$188.69K	New position	0.00	43.88K
Common Stock Indirect	6/6/2025	S · Sale	−43.88K	$10.21	$448.04K	New position	43.88K	0.00
Total			+0.00		-$918.08K

Derivative Transactions6

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

8.40K shares

−8.40K

Strike price

4.3

Held after

51.60K

Exercisable

—

6/4/2025

Stock Option (Right to Buy)

Indirect

M · Option Exercise

Converts to

Common Stock

43.88K shares

−43.88K

Strike price

4.3

Held after

269.56K

Exercisable

—

6/4/2025

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

8.40K shares

−8.40K

Strike price

4.3

Held after

43.20K

Exercisable

—

6/5/2025

Stock Option (Right to Buy)

Indirect

M · Option Exercise

Converts to

Common Stock

43.88K shares

−43.88K

Strike price

4.3

Held after

225.68K

Exercisable

—

6/5/2025

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

8.40K shares

−8.40K

Strike price

4.3

Held after

34.80K

Exercisable

—

6/6/2025

Stock Option (Right to Buy)

Indirect

M · Option Exercise

Converts to

Common Stock

43.88K shares

−43.88K

Strike price

4.3

Held after

181.79K

Exercisable

—

6/6/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock8.40K shares	6/4/2025	M · Option Exercise	−8.40K	4.3	—	51.60K
Stock Option (Right to Buy) Indirect	Common Stock43.88K shares	6/4/2025	M · Option Exercise	−43.88K	4.3	—	269.56K
Stock Option (Right to Buy) Direct	Common Stock8.40K shares	6/5/2025	M · Option Exercise	−8.40K	4.3	—	43.20K
Stock Option (Right to Buy) Indirect	Common Stock43.88K shares	6/5/2025	M · Option Exercise	−43.88K	4.3	—	225.68K
Stock Option (Right to Buy) Direct	Common Stock8.40K shares	6/6/2025	M · Option Exercise	−8.40K	4.3	—	34.80K
Stock Option (Right to Buy) Indirect	Common Stock43.88K shares	6/6/2025	M · Option Exercise	−43.88K	4.3	—	181.79K