DAYNO JEFFREY M. (Chief Medical Officer) exercised options at HARMONY BIOSCIENCES HOLDINGS, INC.

Option exercise — a mechanical event triggered by vesting or expiry. Not a discretionary conviction trade.

M · 2 exercises

DAYNO JEFFREY M.

Filed: 1/26/2026ACC: 0001615993-26-000002

InsiderDAYNO JEFFREY M.CIK 1615993

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IssuerHARMONY BIOSCIENCES HOLDINGS, INC.CIK 1802665

Officer· Chief Medical Officer

Since Aug 2020

+227.06K

Net shares

Net buyer

$384.4K

Total sold

Open market trades

0B · 0S

Total transactions

261K acquired · 33.94K disposed

Non-Derivative Transactions4

Common Stock

Direct

M · Option Exercise

+10.50K

Price / share

—

Trade value

—

% of position

New position

1/24/2026

0.00→10.50K

Common Stock

Direct

F · Tax Withholding

−4.79K

Price / share

$36.82

Trade value

$176.18K

% of position

45.6%

1/24/2026

10.50K→5.71K

Common Stock

Direct

M · Option Exercise

+13K

Price / share

—

Trade value

—

% of position

New position

1/25/2026

0.00→13K

Common Stock

Direct

F · Tax Withholding

−5.65K

Price / share

$36.82

Trade value

$208.18K

% of position

43.5%

1/25/2026

13K→7.35K

Total

Net shares

+13.06K

Net value

-$384.36K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	1/24/2026	M · Option Exercise	+10.50K	—	—	New position	0.00	10.50K
Common Stock Direct	1/24/2026	F · Tax Withholding	−4.79K	$36.82	$176.18K	45.6%	10.50K	5.71K
Common Stock Direct	1/25/2026	M · Option Exercise	+13K	—	—	New position	0.00	13K
Common Stock Direct	1/25/2026	F · Tax Withholding	−5.65K	$36.82	$208.18K	43.5%	13K	7.35K
Total			+13.06K		-$384.36K

Derivative Transactions4

Stock Option

Direct

A · Award

Converts to

Common Stock

184.60K shares

+184.60K

Strike price

36.76

Held after

184.60K

Exercisable

—

1/22/2026

Restricted Stock Units

Direct

A · Award

Converts to

Common Stock

52.90K shares

+52.90K

Strike price

Held after

52.90K

Exercisable

—

1/22/2026

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

10.50K shares

−10.50K

Strike price

Held after

21K

Exercisable

—

1/24/2026

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

13K shares

−13K

Strike price

Held after

39K

Exercisable

—

1/25/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option Direct	Common Stock184.60K shares	1/22/2026	A · Award	+184.60K	36.76	—	184.60K
Restricted Stock Units Direct	Common Stock52.90K shares	1/22/2026	A · Award	+52.90K		—	52.90K
Restricted Stock Units Direct	Common Stock10.50K shares	1/24/2026	M · Option Exercise	−10.50K		—	21K
Restricted Stock Units Direct	Common Stock13K shares	1/25/2026	M · Option Exercise	−13K		—	39K