BUSH TIA L (Chief Quality Officer) reported 1 transaction at CENTESSA PHARMACEUTICALS PLC

Review the transaction codes below to understand the nature of each event.

BUSH TIA L

Filed: 6/24/2026ACC: 0001470831-26-000621

InsiderBUSH TIA LCIK 1863418

→

IssuerCENTESSA PHARMACEUTICALS PLCCIK 1847903

Officer· Chief Quality Officer

Since May 2021

-1.09M

Net shares

Net seller

$0.00

Total acquired

Open market trades

0B · 0S

Total transactions

1.09M disposed

Non-Derivative Transactions1

Ordinary Shares

Direct

D · Disposition

−147.95K

Price / share

—

Trade value

—

% of position

New position

6/24/2026

147.95K→0.00

Total

Net shares

−147.95K

Net value

$0.00

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Ordinary Shares Direct	6/24/2026	D · Disposition	−147.95K	—	—	New position	147.95K	0.00
Total			−147.95K		$0.00

Derivative Transactions6

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

360.34K shares

−360.34K

Strike price

9.42

Held after

0.00

Exercisable

—

6/24/2026

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

140K shares

−140K

Strike price

9.53

Held after

0.00

Exercisable

—

6/24/2026

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

27.19K shares

−27.19K

Strike price

3.85

Held after

0.00

Exercisable

—

6/24/2026

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

145.21K shares

−145.21K

Strike price

8.01

Held after

0.00

Exercisable

—

6/24/2026

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

125K shares

−125K

Strike price

16.90

Held after

0.00

Exercisable

—

6/24/2026

Share Option (right to buy)

Direct

D · Disposition

Converts to

Ordinary Shares

140K shares

−140K

Strike price

25.19

Held after

0.00

Exercisable

—

6/24/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable
Share Option (right to buy) Direct	Ordinary Shares360.34K shares	6/24/2026	D · Disposition	−360.34K	9.42	—
Share Option (right to buy) Direct	Ordinary Shares140K shares	6/24/2026	D · Disposition	−140K	9.53	—
Share Option (right to buy) Direct	Ordinary Shares27.19K shares	6/24/2026	D · Disposition	−27.19K	3.85	—
Share Option (right to buy) Direct	Ordinary Shares145.21K shares	6/24/2026	D · Disposition	−145.21K	8.01	—
Share Option (right to buy) Direct	Ordinary Shares125K shares	6/24/2026	D · Disposition	−125K	16.90	—
Share Option (right to buy) Direct	Ordinary Shares140K shares	6/24/2026	D · Disposition	−140K	25.19	—