BURROWS SCOTT L

PrivateCIK: 1853327
Location

WALTHAM, MA

BURROWS SCOTT L (Chief Financial Officer) sold 23.9% of their position (25K shares) of SPYRE THERAPEUTICS, INC. on the open market

Open‑market sale worth $2.26M — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 6 sales
InsiderBURROWS SCOTT LCIK 1853327
→
IssuerSPYRE THERAPEUTICS, INC.CIK 1636282
Officer· Chief Financial Officer
Since Mar 2026
-25K
Net shares
Net seller
$2.26M
Total sold
6
Open market trades
0B · 6S
10
Total transactions
25K acquired · 50K disposed
Non-Derivative Transactions8

Common Stock

Direct
M · Option Exercise

Shares

+17.50K

Price / share

$14.50

Trade value

$253.75K

% of position

21.9%
9/30/2026
79.76K→97.26K

Common Stock

Direct
S · Sale

Shares

−17.50K

Price / share

$89.89

Trade value

$1.57M

% of position

18.0%
9/30/2026
97.26K→79.76K

Common Stock

Direct
M · Option Exercise

Shares

+7.50K

Price / share

$14.50

Trade value

$108.75K

% of position

9.4%
10/1/2026
79.76K→87.26K

Common Stock

Direct
S · Sale

Shares

−600.00

Price / share

$89.07

Trade value

$53.44K

% of position

0.7%
10/1/2026
87.26K→86.66K

Common Stock

Direct
S · Sale

Shares

−1.50K

Price / share

$90.27

Trade value

$135.41K

% of position

1.7%
10/1/2026
86.66K→85.16K

Common Stock

Direct
S · Sale

Shares

−2.10K

Price / share

$91.92

Trade value

$193.03K

% of position

2.5%
10/1/2026
85.16K→83.06K

Common Stock

Direct
S · Sale

Shares

−3.07K

Price / share

$92.95

Trade value

$285.45K

% of position

3.7%
10/1/2026
83.06K→79.99K

Common Stock

Direct
S · Sale

Shares

−229.00

Price / share

$93.57

Trade value

$21.43K

% of position

0.3%
10/1/2026
79.99K→79.76K
Total

Net shares

+0.00

Net value

-$1.90M

Derivative Transactions2

Stock Option (Right to Buy)

Direct
M · Option Exercise
Converts to

Common Stock

17.50K shares

Shares

−17.50K

Strike price

14.50

Held after

319.86K

Exercisable

—

9/30/2026

Stock Option (Right to Buy)

Direct
M · Option Exercise
Converts to

Common Stock

7.50K shares

Shares

−7.50K

Strike price

14.50

Held after

312.36K

Exercisable

—

10/1/2026
BURROWS SCOTT L — Insider Transaction (Form 4) Filed Oct 3, 2026 | Finecho