BURROWS SCOTT L

PrivateCIK: 1853327
Location

WALTHAM, MA

BURROWS SCOTT L (Chief Financial Officer) sold 7.1% of their position (7.50K shares) of SPYRE THERAPEUTICS, INC. on the open market

Open‑market sale worth $716.8K — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 3 sales
InsiderBURROWS SCOTT LCIK 1853327
IssuerSPYRE THERAPEUTICS, INC.CIK 1636282
Officer· Chief Financial Officer
Since Mar 2026
-7.50K
Net shares
Net seller
$716.8K
Total sold
3
Open market trades
0B · 3S
5
Total transactions
7.50K acquired · 15K disposed
Non-Derivative Transactions4

Common Stock

Direct
M · Option Exercise

Shares

+7.50K

Price / share

$14.50

Trade value

$108.75K

% of position

7.7%
8/3/2026
97.99K105.49K

Common Stock

Direct
S · Sale

Shares

5.10K

Price / share

$95.21

Trade value

$485.57K

% of position

4.8%
8/3/2026
105.49K100.39K

Common Stock

Direct
S · Sale

Shares

2.30K

Price / share

$96.30

Trade value

$221.49K

% of position

2.3%
8/3/2026
100.39K98.09K

Common Stock

Direct
S · Sale

Shares

100.00

Price / share

$97.10

Trade value

$9.71K

% of position

0.1%
8/3/2026
98.09K97.99K
Total

Net shares

+0.00

Net value

-$608.02K

Derivative Transactions1

Stock Option (Right to Buy)

Direct
M · Option Exercise
Converts to

Common Stock

7.50K shares

Shares

7.50K

Strike price

14.50

Held after

344.86K

Exercisable

8/3/2026