Filed: 5/15/2026ACC: 0001104659-26-062547
📋 What this filing means
BAKER BROS. ADVISORS LP filed this quarterly 13F‑HR report disclosing 84 equity positions with a total reported market value of $17.42B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
84
Positions
$17.42B
Total AUM (reported)
420.43M
Total Shares
Allocation by class
COM$12.33B70.8%
SPONSORED ADS$2.91B16.7%
COM PAR $.01$1.21B7.0%
SHS$602.25M3.5%
ORD SHS CL A$136.08M0.8%
NOTE 2.75% 8/1/2031$74.87M0.4%
COM SHS$60.11M0.3%
Portfolio Concentration
Top 3$6.72B38.6%
4–10$6.08B34.9%
11–25$3.06B17.6%
Rest$1.56B9.0%
Top 3 weight
38.6%
Top 10 weight
73.5%
Voting Authority Distribution
Total shares with voting rights: 420.43M
Sole
Full voting authority
420.43M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole84
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings84
Rows:
Incyte Corporation
SOLEShares30.74M
TypeSH
Market value$2.89B
16.62%
Sole
30.74M
Shared
0.00
None
0.00
BeOne Medicines Ltd.
SOLEShares8.80M
TypeSH
Market value$2.61B
15.00%
Sole
8.80M
Shared
0.00
None
0.00
Insmed Incorporated
SOLEShares7.42M
TypeSH
Market value$1.21B
6.97%
Sole
7.42M
Shared
0.00
None
0.00
Madrigal Pharmaceuticals, Inc.
SOLEShares2.14M
TypeSH
Market value$1.12B
6.44%
Sole
2.14M
Shared
0.00
None
0.00
ACADIA Pharmaceuticals Inc.
SOLEShares42.90M
TypeSH
Market value$954.88M
5.48%
Sole
42.90M
Shared
0.00
None
0.00
Revolution Medicines, Inc.
SOLEShares9.56M
TypeSH
Market value$929.26M
5.34%
Sole
9.56M
Shared
0.00
None
0.00
Celcuity Inc.
SOLEShares7.92M
TypeSH
Market value$903.51M
5.19%
Sole
7.92M
Shared
0.00
None
0.00
Kodiak Sciences Inc.
SOLEShares19.92M
TypeSH
Market value$759.32M
4.36%
Sole
19.92M
Shared
0.00
None
0.00
Kymera Therapeutics, Inc.
SOLEShares8.66M
TypeSH
Market value$721.06M
4.14%
Sole
8.66M
Shared
0.00
None
0.00
Summit Therapeutics Inc.
SOLEShares36.39M
TypeSH
Market value$689.97M
3.96%
Sole
36.39M
Shared
0.00
None
0.00
Praxis Precision Medicines, Inc.
SOLEShares1.75M
TypeSH
Market value$564.86M
3.24%
Sole
1.75M
Shared
0.00
None
0.00
Rhythm Pharmaceuticals, Inc.
SOLEShares5.60M
TypeSH
Market value$487.42M
2.80%
Sole
5.60M
Shared
0.00
None
0.00
Alkermes plc
SOLEShares10.01M
TypeSH
Market value$354.03M
2.03%
Sole
10.01M
Shared
0.00
None
0.00
GRAIL, Inc.
SOLEShares4.03M
TypeSH
Market value$208.20M
1.20%
Sole
4.03M
Shared
0.00
None
0.00
Edgewise Therapeutics, Inc.
SOLEShares6.58M
TypeSH
Market value$207.14M
1.19%
Sole
6.58M
Shared
0.00
None
0.00
Ionis Pharmaceuticals, Inc.
SOLEShares2.05M
TypeSH
Market value$153.76M
0.88%
Sole
2.05M
Shared
0.00
None
0.00
Kiniksa Pharmaceuticals International, plc
SOLEShares2.83M
TypeSH
Market value$136.08M
0.78%
Sole
2.83M
Shared
0.00
None
0.00
Immunovant, Inc.
SOLEShares5.46M
TypeSH
Market value$135.57M
0.78%
Sole
5.46M
Shared
0.00
None
0.00
Roivant Sciences Ltd.
SOLEShares4.87M
TypeSH
Market value$134.84M
0.77%
Sole
4.87M
Shared
0.00
None
0.00
IDEAYA Biosciences, Inc.
SOLEShares3.95M
TypeSH
Market value$131.50M
0.76%
Sole
3.95M
Shared
0.00
None
0.00
Arrowhead Pharmaceuticals, Inc.
SOLEShares1.99M
TypeSH
Market value$124.95M
0.72%
Sole
1.99M
Shared
0.00
None
0.00
Stoke Therapeutics, Inc.
SOLEShares3.34M
TypeSH
Market value$108.64M
0.62%
Sole
3.34M
Shared
0.00
None
0.00
Immatics N.V.
SOLEShares10.92M
TypeSH
Market value$107.42M
0.62%
Sole
10.92M
Shared
0.00
None
0.00
AbCellera Biologics Inc.
SOLEShares30.28M
TypeSH
Market value$105.66M
0.61%
Sole
30.28M
Shared
0.00
None
0.00
Abivax S.A.
SOLEShares875.80K
TypeSH
Market value$97.52M
0.56%
Sole
875.80K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
Incyte CorporationSOLE | COM | 30.74M | SH | $2.89B 16.62% | 30.74M | 0.00 | 0.00 |
BeOne Medicines Ltd.SOLE | SPONSORED ADS | 8.80M | SH | $2.61B 15.00% | 8.80M | 0.00 | 0.00 |
Insmed IncorporatedSOLE | COM PAR $.01 | 7.42M | SH | $1.21B 6.97% | 7.42M | 0.00 | 0.00 |
Madrigal Pharmaceuticals, Inc.SOLE | COM | 2.14M | SH | $1.12B 6.44% | 2.14M | 0.00 | 0.00 |
ACADIA Pharmaceuticals Inc.SOLE | COM | 42.90M | SH | $954.88M 5.48% | 42.90M | 0.00 | 0.00 |
Revolution Medicines, Inc.SOLE | COM | 9.56M | SH | $929.26M 5.34% | 9.56M | 0.00 | 0.00 |
Celcuity Inc.SOLE | COM | 7.92M | SH | $903.51M 5.19% | 7.92M | 0.00 | 0.00 |
Kodiak Sciences Inc.SOLE | COM | 19.92M | SH | $759.32M 4.36% | 19.92M | 0.00 | 0.00 |
Kymera Therapeutics, Inc.SOLE | COM | 8.66M | SH | $721.06M 4.14% | 8.66M | 0.00 | 0.00 |
Summit Therapeutics Inc.SOLE | COM | 36.39M | SH | $689.97M 3.96% | 36.39M | 0.00 | 0.00 |
Praxis Precision Medicines, Inc.SOLE | COM | 1.75M | SH | $564.86M 3.24% | 1.75M | 0.00 | 0.00 |
Rhythm Pharmaceuticals, Inc.SOLE | COM | 5.60M | SH | $487.42M 2.80% | 5.60M | 0.00 | 0.00 |
Alkermes plcSOLE | SHS | 10.01M | SH | $354.03M 2.03% | 10.01M | 0.00 | 0.00 |
GRAIL, Inc.SOLE | COM | 4.03M | SH | $208.20M 1.20% | 4.03M | 0.00 | 0.00 |
Edgewise Therapeutics, Inc.SOLE | COM | 6.58M | SH | $207.14M 1.19% | 6.58M | 0.00 | 0.00 |
Ionis Pharmaceuticals, Inc.SOLE | COM | 2.05M | SH | $153.76M 0.88% | 2.05M | 0.00 | 0.00 |
Kiniksa Pharmaceuticals International, plcSOLE | ORD SHS CL A | 2.83M | SH | $136.08M 0.78% | 2.83M | 0.00 | 0.00 |
Immunovant, Inc.SOLE | COM | 5.46M | SH | $135.57M 0.78% | 5.46M | 0.00 | 0.00 |
Roivant Sciences Ltd.SOLE | SHS | 4.87M | SH | $134.84M 0.77% | 4.87M | 0.00 | 0.00 |
IDEAYA Biosciences, Inc.SOLE | COM | 3.95M | SH | $131.50M 0.76% | 3.95M | 0.00 | 0.00 |
Arrowhead Pharmaceuticals, Inc.SOLE | COM | 1.99M | SH | $124.95M 0.72% | 1.99M | 0.00 | 0.00 |
Stoke Therapeutics, Inc.SOLE | COM | 3.34M | SH | $108.64M 0.62% | 3.34M | 0.00 | 0.00 |
Immatics N.V.SOLE | SHS | 10.92M | SH | $107.42M 0.62% | 10.92M | 0.00 | 0.00 |
AbCellera Biologics Inc.SOLE | COM | 30.28M | SH | $105.66M 0.61% | 30.28M | 0.00 | 0.00 |
Abivax S.A.SOLE | SPONSORED ADS | 875.80K | SH | $97.52M 0.56% | 875.80K | 0.00 | 0.00 |
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