Filed: 11/14/2025ACC: 0001012975-25-000787
📋 What this filing means
ARCH VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 9 equity positions with a total reported market value of $492.36M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
9
Positions
$492.36M
Total AUM (reported)
47.52M
Total Shares
Allocation by class
COM$447.56M90.9%
COM NEW$44.81M9.1%
Portfolio Concentration
Top 3$327.77M66.6%
4–10$164.60M33.4%
Top 3 weight
66.6%
Top 10 weight
100.0%
Voting Authority Distribution
Total shares with voting rights: 47.52M
Sole
Full voting authority
0.00
shares
% of voting shares0.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
47.52M
shares
% of voting shares100.0%
Investment Discretion (by position count)
Sole9
Shared0
Other0
Dominant voting typeNone · 100.0% of voting shares
Institutional Holdings9
Rows:
RAPPORT THERAPEUTICS INC.
SOLEShares3.73M
TypeSH
Market value$110.74M
22.49%
Sole
0.00
Shared
0.00
None
3.73M
BEAM THERAPEUTICS INC.
SOLEShares4.54M
TypeSH
Market value$110.19M
22.38%
Sole
0.00
Shared
0.00
None
4.54M
MAZE THERAPEUTICS INC.
SOLEShares4.12M
TypeSH
Market value$106.83M
21.70%
Sole
0.00
Shared
0.00
None
4.12M
VIR BIOTECHNOLOGY INC.
SOLEShares12.92M
TypeSH
Market value$73.75M
14.98%
Sole
0.00
Shared
0.00
None
12.92M
LYELL IMMUNOPHARMA INC.
SOLEShares2.76M
TypeSH
Market value$44.81M
9.10%
Sole
0.00
Shared
0.00
None
2.76M
ERASCA INC.
SOLEShares11.06M
TypeSH
Market value$24.10M
4.89%
Sole
0.00
Shared
0.00
None
11.06M
GOSSAMER BIO INC.
SOLEShares8.06M
TypeSH
Market value$21.19M
4.30%
Sole
0.00
Shared
0.00
None
8.06M
Q32 BIO INC.
SOLEShares320.48K
TypeSH
Market value$634.6K
0.13%
Sole
0.00
Shared
0.00
None
320.48K
CERO THERAPEUTICS HOLDINGS INC.
SOLEShares22.39K
TypeSH
Market value$114.0K
0.02%
Sole
0.00
Shared
0.00
None
22.39K
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
RAPPORT THERAPEUTICS INC.SOLE | COM | 3.73M | SH | $110.74M 22.49% | 0.00 | 0.00 | 3.73M |
BEAM THERAPEUTICS INC.SOLE | COM | 4.54M | SH | $110.19M 22.38% | 0.00 | 0.00 | 4.54M |
MAZE THERAPEUTICS INC.SOLE | COM | 4.12M | SH | $106.83M 21.70% | 0.00 | 0.00 | 4.12M |
VIR BIOTECHNOLOGY INC.SOLE | COM | 12.92M | SH | $73.75M 14.98% | 0.00 | 0.00 | 12.92M |
LYELL IMMUNOPHARMA INC.SOLE | COM NEW | 2.76M | SH | $44.81M 9.10% | 0.00 | 0.00 | 2.76M |
ERASCA INC.SOLE | COM | 11.06M | SH | $24.10M 4.89% | 0.00 | 0.00 | 11.06M |
GOSSAMER BIO INC.SOLE | COM | 8.06M | SH | $21.19M 4.30% | 0.00 | 0.00 | 8.06M |
Q32 BIO INC.SOLE | COM | 320.48K | SH | $634.6K 0.13% | 0.00 | 0.00 | 320.48K |
CERO THERAPEUTICS HOLDINGS INC.SOLE | COM | 22.39K | SH | $114.0K 0.02% | 0.00 | 0.00 | 22.39K |