AFEYAN NOUBAR purchased 4.69M shares of GENERATE BIOMEDICINES, INC. on the open market

Open‑market purchase worth $75.00M. The strongest form of insider conviction signal.

P · 3 purchases

AFEYAN NOUBAR

Filed: 3/2/2026ACC: 0001193125-26-085888

InsiderAFEYAN NOUBARCIK 1222012

→

IssuerGENERATE BIOMEDICINES, INC.CIK 2100782

Director10% Owner

Since Feb 2026

-12.39M

Net shares

Net seller

$75.00M

Total acquired

Open market trades

3B · 0S

Total transactions

37.69M acquired · 50.08M disposed

Non-Derivative Transactions8

Common Stock

Indirect

C · Conversion

+12.72M

Price / share

—

Trade value

—

% of position

New position

3/2/2026

0.00→12.72M

Common Stock

Indirect

C · Conversion

+13.70M

Price / share

—

Trade value

—

% of position

New position

3/2/2026

0.00→13.70M

Common Stock

Indirect

C · Conversion

+987.49K

Price / share

—

Trade value

—

% of position

New position

3/2/2026

0.00→987.49K

Common Stock

Indirect

C · Conversion

+2.78M

Price / share

—

Trade value

—

% of position

New position

3/2/2026

0.00→2.78M

Common Stock

Indirect

C · Conversion

+2.78M

Price / share

—

Trade value

—

% of position

New position

3/2/2026

0.00→2.78M

Common Stock

Indirect

P · Purchase

+1.56M

Price / share

$16.00

Trade value

$25M

% of position

11.4%

3/2/2026

13.70M→15.26M

Common Stock

Indirect

P · Purchase

+1.56M

Price / share

$16.00

Trade value

$25M

% of position

56.3%

3/2/2026

2.78M→4.34M

Common Stock

Indirect

P · Purchase

+1.56M

Price / share

$16.00

Trade value

$25M

% of position

New position

3/2/2026

0.00→1.56M

Total

Net shares

+37.66M

Net value

$75M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Indirect	3/2/2026	C · Conversion	+12.72M	—	—	New position	0.00	12.72M
Common Stock Indirect	3/2/2026	C · Conversion	+13.70M	—	—	New position	0.00	13.70M
Common Stock Indirect	3/2/2026	C · Conversion	+987.49K	—	—	New position	0.00	987.49K
Common Stock Indirect	3/2/2026	C · Conversion	+2.78M	—	—	New position	0.00	2.78M
Common Stock Indirect	3/2/2026	C · Conversion	+2.78M	—	—	New position	0.00	2.78M
Common Stock Indirect	3/2/2026	P · Purchase	+1.56M	$16.00	$25M	11.4%	13.70M	15.26M
Common Stock Indirect	3/2/2026	P · Purchase	+1.56M	$16.00	$25M	56.3%	2.78M	4.34M
Common Stock Indirect	3/2/2026	P · Purchase	+1.56M	$16.00	$25M	New position	0.00	1.56M
Total			+37.66M		$75M

Derivative Transactions11

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

29.56K shares

+29.56K

Strike price

Held after

29.56K

Exercisable

—

2/26/2026

Series A Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

12.17M shares

−18.48M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series A Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

11.20M shares

−17.02M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series A Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

987.49K shares

−1.50M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series B Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

555.55K shares

−843.88K

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series B Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

833.33K shares

−1.27M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series B Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

1.94M shares

−2.95M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series B Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

1.39M shares

−2.11M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series C Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

1.67M shares

−2.53M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series C Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

833.33K shares

−1.27M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Series C Preferred Stock

Indirect

C · Conversion

Converts to

Common Stock

1.39M shares

−2.11M

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock29.56K shares	2/26/2026	A · Award	+29.56K	16	—	29.56K
Series A Preferred Stock Indirect	Common Stock12.17M shares	3/2/2026	C · Conversion	−18.48M		—	0.00
Series A Preferred Stock Indirect	Common Stock11.20M shares	3/2/2026	C · Conversion	−17.02M		—	0.00
Series A Preferred Stock Indirect	Common Stock987.49K shares	3/2/2026	C · Conversion	−1.50M		—	0.00
Series B Preferred Stock Indirect	Common Stock555.55K shares	3/2/2026	C · Conversion	−843.88K		—	0.00
Series B Preferred Stock Indirect	Common Stock833.33K shares	3/2/2026	C · Conversion	−1.27M		—	0.00
Series B Preferred Stock Indirect	Common Stock1.94M shares	3/2/2026	C · Conversion	−2.95M		—	0.00
Series B Preferred Stock Indirect	Common Stock1.39M shares	3/2/2026	C · Conversion	−2.11M		—	0.00
Series C Preferred Stock Indirect	Common Stock1.67M shares	3/2/2026	C · Conversion	−2.53M		—	0.00
Series C Preferred Stock Indirect	Common Stock833.33K shares	3/2/2026	C · Conversion	−1.27M		—	0.00
Series C Preferred Stock Indirect	Common Stock1.39M shares	3/2/2026	C · Conversion	−2.11M		—	0.00

Non-Derivative Holdings (Post-Transaction)1

Common Stock

Indirect

Shares owned25.02M

Total

25.02M indirect25.02M

Security Title	Shares Owned	Ownership Type
Common Stock	25.02M	Indirect
Total	25.02M	25.02M indirect

Derivative Holdings (Post-Transaction)0

No derivative holdings reported