Filed: 11/14/2024ACC: 0001104659-24-118921
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 28 equity positions with a total reported market value of $484.00M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
28
Positions
$484.00M
Total AUM (reported)
47.91M
Total Shares
Allocation by class
COM$348.71M72.0%
COM NEW$88.03M18.2%
SPONSORED ADS$20.55M4.2%
CLASS A ORD$14.23M2.9%
ADS$8.66M1.8%
ORDINARY SHARES$3.83M0.8%
Portfolio Concentration
Top 3$153.96M31.8%
4–10$175.80M36.3%
11–25$149.37M30.9%
Rest$4.88M1.0%
Top 3 weight
31.8%
Top 10 weight
68.1%
Voting Authority Distribution
Total shares with voting rights: 47.91M
Sole
Full voting authority
47.91M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole28
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings28
Rows:
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$70.45M
14.55%
Sole
4.41M
Shared
0.00
None
0.00
ENLIVEN THERAPEUTICS INC
SOLEShares1.75M
TypeSH
Market value$44.75M
9.25%
Sole
1.75M
Shared
0.00
None
0.00
SKYE BIOSCIENCE INC
SOLEShares9.91M
TypeSH
Market value$38.76M
8.01%
Sole
9.91M
Shared
0.00
None
0.00
ARTIVA BIOTHERAPEUTICS INC
SOLEShares2.35M
TypeSH
Market value$36.36M
7.51%
Sole
2.35M
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS INC
SOLEShares1.23M
TypeSH
Market value$33.72M
6.97%
Sole
1.23M
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares478.97K
TypeSH
Market value$23.93M
4.95%
Sole
478.97K
Shared
0.00
None
0.00
TYRA BIOSCIENCES INC
SOLEShares939.30K
TypeSH
Market value$22.08M
4.56%
Sole
939.30K
Shared
0.00
None
0.00
CENTESSA PHARMACEUTICALS PLC
SOLEShares1.28M
TypeSH
Market value$20.55M
4.25%
Sole
1.28M
Shared
0.00
None
0.00
TECTONIC THERAPEUTIC INC
SOLEShares646.52K
TypeSH
Market value$19.59M
4.05%
Sole
646.52K
Shared
0.00
None
0.00
PRAXIS PRECISION MEDICINES I
SOLEShares340K
TypeSH
Market value$19.56M
4.04%
Sole
340K
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares497.27K
TypeSH
Market value$16.90M
3.49%
Sole
497.27K
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares736.60K
TypeSH
Market value$16.76M
3.46%
Sole
736.60K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares237.56K
TypeSH
Market value$15.04M
3.11%
Sole
237.56K
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares797.60K
TypeSH
Market value$14.77M
3.05%
Sole
797.60K
Shared
0.00
None
0.00
ERASCA INC
SOLEShares5.41M
TypeSH
Market value$14.76M
3.05%
Sole
5.41M
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares282.31K
TypeSH
Market value$14.23M
2.94%
Sole
282.31K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$11.98M
2.48%
Sole
357.73K
Shared
0.00
None
0.00
SILENCE THERAPEUTICS PLC
SOLEShares476.20K
TypeSH
Market value$8.66M
1.79%
Sole
476.20K
Shared
0.00
None
0.00
EYEPOINT PHARMACEUTICALS INC
SOLEShares1.05M
TypeSH
Market value$8.39M
1.73%
Sole
1.05M
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares561.85K
TypeSH
Market value$6.07M
1.25%
Sole
561.85K
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$5.47M
1.13%
Sole
1.20M
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$4.45M
0.92%
Sole
6.36M
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$4.25M
0.88%
Sole
3.63M
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares572.66K
TypeSH
Market value$3.83M
0.79%
Sole
572.66K
Shared
0.00
None
0.00
ADVERUM BIOTECHNOLOGIES INC
SOLEShares541.67K
TypeSH
Market value$3.80M
0.79%
Sole
541.67K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $70.45M 14.55% | 4.41M | 0.00 | 0.00 |
ENLIVEN THERAPEUTICS INCSOLE | COM | 1.75M | SH | $44.75M 9.25% | 1.75M | 0.00 | 0.00 |
SKYE BIOSCIENCE INCSOLE | COM NEW | 9.91M | SH | $38.76M 8.01% | 9.91M | 0.00 | 0.00 |
ARTIVA BIOTHERAPEUTICS INCSOLE | COM | 2.35M | SH | $36.36M 7.51% | 2.35M | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INCSOLE | COM | 1.23M | SH | $33.72M 6.97% | 1.23M | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 478.97K | SH | $23.93M 4.95% | 478.97K | 0.00 | 0.00 |
TYRA BIOSCIENCES INCSOLE | COM | 939.30K | SH | $22.08M 4.56% | 939.30K | 0.00 | 0.00 |
CENTESSA PHARMACEUTICALS PLCSOLE | SPONSORED ADS | 1.28M | SH | $20.55M 4.25% | 1.28M | 0.00 | 0.00 |
TECTONIC THERAPEUTIC INCSOLE | COM | 646.52K | SH | $19.59M 4.05% | 646.52K | 0.00 | 0.00 |
PRAXIS PRECISION MEDICINES ISOLE | COM NEW | 340K | SH | $19.56M 4.04% | 340K | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 497.27K | SH | $16.90M 3.49% | 497.27K | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 736.60K | SH | $16.76M 3.46% | 736.60K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 237.56K | SH | $15.04M 3.11% | 237.56K | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 797.60K | SH | $14.77M 3.05% | 797.60K | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 5.41M | SH | $14.76M 3.05% | 5.41M | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 282.31K | SH | $14.23M 2.94% | 282.31K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $11.98M 2.48% | 357.73K | 0.00 | 0.00 |
SILENCE THERAPEUTICS PLCSOLE | ADS | 476.20K | SH | $8.66M 1.79% | 476.20K | 0.00 | 0.00 |
EYEPOINT PHARMACEUTICALS INCSOLE | COM NEW | 1.05M | SH | $8.39M 1.73% | 1.05M | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 561.85K | SH | $6.07M 1.25% | 561.85K | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $5.47M 1.13% | 1.20M | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $4.45M 0.92% | 6.36M | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $4.25M 0.88% | 3.63M | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 572.66K | SH | $3.83M 0.79% | 572.66K | 0.00 | 0.00 |
ADVERUM BIOTECHNOLOGIES INCSOLE | COM NEW | 541.67K | SH | $3.80M 0.79% | 541.67K | 0.00 | 0.00 |
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