Filed: 8/14/2024ACC: 0001104659-24-089661
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 28 equity positions with a total reported market value of $447.09M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
28
Positions
$447.09M
Total AUM (reported)
46.11M
Total Shares
Allocation by class
COM$289.56M64.8%
COM NEW$118.16M26.4%
CLASS A ORD$12.41M2.8%
SPONSORED ADS$11.24M2.5%
ADS$9.05M2.0%
ORDINARY SHARES$6.68M1.5%
Portfolio Concentration
Top 3$205.37M45.9%
4–10$123.46M27.6%
11–25$115.15M25.8%
Rest$3.12M0.7%
Top 3 weight
45.9%
Top 10 weight
73.5%
Voting Authority Distribution
Total shares with voting rights: 46.11M
Sole
Full voting authority
46.11M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole28
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings28
Rows:
SKYE BIOSCIENCE INC
SOLEShares10.18M
TypeSH
Market value$81.54M
18.24%
Sole
10.18M
Shared
0.00
None
0.00
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$62.82M
14.05%
Sole
4.41M
Shared
0.00
None
0.00
ENLIVEN THERAPEUTICS INC
SOLEShares2.61M
TypeSH
Market value$61.02M
13.65%
Sole
2.61M
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS INC
SOLEShares1.23M
TypeSH
Market value$31.91M
7.14%
Sole
1.23M
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares497.27K
TypeSH
Market value$18.40M
4.12%
Sole
497.27K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares469.97K
TypeSH
Market value$16.31M
3.65%
Sole
469.97K
Shared
0.00
None
0.00
TYRA BIOSCIENCES INC
SOLEShares939.30K
TypeSH
Market value$15.02M
3.36%
Sole
939.30K
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares797.60K
TypeSH
Market value$14.99M
3.35%
Sole
797.60K
Shared
0.00
None
0.00
PRAXIS PRECISION MEDICINES I
SOLEShares340K
TypeSH
Market value$14.06M
3.15%
Sole
340K
Shared
0.00
None
0.00
ERASCA INC
SOLEShares5.41M
TypeSH
Market value$12.76M
2.85%
Sole
5.41M
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares237.56K
TypeSH
Market value$12.59M
2.82%
Sole
237.56K
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares282.31K
TypeSH
Market value$12.41M
2.78%
Sole
282.31K
Shared
0.00
None
0.00
CENTESSA PHARMACEUTICALS PLC
SOLEShares1.25M
TypeSH
Market value$11.24M
2.51%
Sole
1.25M
Shared
0.00
None
0.00
TECTONIC THERAPEUTIC INC
SOLEShares646.52K
TypeSH
Market value$10.65M
2.38%
Sole
646.52K
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares736.60K
TypeSH
Market value$9.58M
2.14%
Sole
736.60K
Shared
0.00
None
0.00
SILENCE THERAPEUTICS PLC
SOLEShares476.20K
TypeSH
Market value$9.05M
2.02%
Sole
476.20K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$8.96M
2.01%
Sole
357.73K
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares572.66K
TypeSH
Market value$6.68M
1.49%
Sole
572.66K
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares790.44K
TypeSH
Market value$6.66M
1.49%
Sole
790.44K
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$6.36M
1.42%
Sole
6.36M
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$5.22M
1.17%
Sole
1.20M
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$4.87M
1.09%
Sole
3.63M
Shared
0.00
None
0.00
Q32 BIO INC
SOLEShares251.99K
TypeSH
Market value$4.52M
1.01%
Sole
251.99K
Shared
0.00
None
0.00
ADVERUM BIOTECHNOLOGIES INC
SOLEShares541.67K
TypeSH
Market value$3.72M
0.83%
Sole
541.67K
Shared
0.00
None
0.00
MERSANA THERAPEUTICS INC
SOLEShares1.30M
TypeSH
Market value$2.62M
0.59%
Sole
1.30M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
SKYE BIOSCIENCE INCSOLE | COM NEW | 10.18M | SH | $81.54M 18.24% | 10.18M | 0.00 | 0.00 |
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $62.82M 14.05% | 4.41M | 0.00 | 0.00 |
ENLIVEN THERAPEUTICS INCSOLE | COM | 2.61M | SH | $61.02M 13.65% | 2.61M | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INCSOLE | COM | 1.23M | SH | $31.91M 7.14% | 1.23M | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 497.27K | SH | $18.40M 4.12% | 497.27K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 469.97K | SH | $16.31M 3.65% | 469.97K | 0.00 | 0.00 |
TYRA BIOSCIENCES INCSOLE | COM | 939.30K | SH | $15.02M 3.36% | 939.30K | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 797.60K | SH | $14.99M 3.35% | 797.60K | 0.00 | 0.00 |
PRAXIS PRECISION MEDICINES ISOLE | COM NEW | 340K | SH | $14.06M 3.15% | 340K | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 5.41M | SH | $12.76M 2.85% | 5.41M | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 237.56K | SH | $12.59M 2.82% | 237.56K | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 282.31K | SH | $12.41M 2.78% | 282.31K | 0.00 | 0.00 |
CENTESSA PHARMACEUTICALS PLCSOLE | SPONSORED ADS | 1.25M | SH | $11.24M 2.51% | 1.25M | 0.00 | 0.00 |
TECTONIC THERAPEUTIC INCSOLE | COM | 646.52K | SH | $10.65M 2.38% | 646.52K | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 736.60K | SH | $9.58M 2.14% | 736.60K | 0.00 | 0.00 |
SILENCE THERAPEUTICS PLCSOLE | ADS | 476.20K | SH | $9.05M 2.02% | 476.20K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $8.96M 2.01% | 357.73K | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 572.66K | SH | $6.68M 1.49% | 572.66K | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 790.44K | SH | $6.66M 1.49% | 790.44K | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $6.36M 1.42% | 6.36M | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $5.22M 1.17% | 1.20M | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $4.87M 1.09% | 3.63M | 0.00 | 0.00 |
Q32 BIO INCSOLE | COM | 251.99K | SH | $4.52M 1.01% | 251.99K | 0.00 | 0.00 |
ADVERUM BIOTECHNOLOGIES INCSOLE | COM NEW | 541.67K | SH | $3.72M 0.83% | 541.67K | 0.00 | 0.00 |
MERSANA THERAPEUTICS INCSOLE | COM | 1.30M | SH | $2.62M 0.59% | 1.30M | 0.00 | 0.00 |
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