Filed: 5/15/2024ACC: 0001104659-24-061973
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 26 equity positions with a total reported market value of $446.63M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
26
Positions
$446.63M
Total AUM (reported)
33.21M
Total Shares
Allocation by class
COM$352.71M79.0%
COM NEW$49.28M11.0%
CLASS A ORD$14.18M3.2%
SPONSORED ADS$14.07M3.1%
ADS$10.29M2.3%
ORDINARY SHARES$6.10M1.4%
Portfolio Concentration
Top 3$167.20M37.4%
4–10$138.73M31.1%
11–25$139.65M31.3%
Rest$1.04M0.2%
Top 3 weight
37.4%
Top 10 weight
68.5%
Voting Authority Distribution
Total shares with voting rights: 33.21M
Sole
Full voting authority
33.21M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole26
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings26
Rows:
ENLIVEN THERAPEUTICS INC
SOLEShares3.84M
TypeSH
Market value$67.47M
15.11%
Sole
3.84M
Shared
0.00
None
0.00
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$62.47M
13.99%
Sole
4.41M
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS INC
SOLEShares1.24M
TypeSH
Market value$37.26M
8.34%
Sole
1.24M
Shared
0.00
None
0.00
MERUS N V
SOLEShares548.83K
TypeSH
Market value$24.71M
5.53%
Sole
548.83K
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares497.27K
TypeSH
Market value$20.87M
4.67%
Sole
497.27K
Shared
0.00
None
0.00
PRAXIS PRECISION MEDICINES I
SOLEShares340K
TypeSH
Market value$20.75M
4.65%
Sole
340K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares237.56K
TypeSH
Market value$19.48M
4.36%
Sole
237.56K
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares797.60K
TypeSH
Market value$18.43M
4.13%
Sole
797.60K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares319.97K
TypeSH
Market value$17.50M
3.92%
Sole
319.97K
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares665.55K
TypeSH
Market value$16.98M
3.80%
Sole
665.55K
Shared
0.00
None
0.00
TYRA BIOSCIENCES INC
SOLEShares939.30K
TypeSH
Market value$15.40M
3.45%
Sole
939.30K
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$15.08M
3.38%
Sole
6.36M
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares282.31K
TypeSH
Market value$14.18M
3.18%
Sole
282.31K
Shared
0.00
None
0.00
CENTESSA PHARMACEUTICALS PLC
SOLEShares1.25M
TypeSH
Market value$14.07M
3.15%
Sole
1.25M
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares736.60K
TypeSH
Market value$12.90M
2.89%
Sole
736.60K
Shared
0.00
None
0.00
SILENCE THERAPEUTICS PLC
SOLEShares476.20K
TypeSH
Market value$10.29M
2.30%
Sole
476.20K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$8.06M
1.80%
Sole
357.73K
Shared
0.00
None
0.00
ZENTALIS PHARMACEUTICALS INC
SOLEShares490K
TypeSH
Market value$7.72M
1.73%
Sole
490K
Shared
0.00
None
0.00
ADVERUM BIOTECHNOLOGIES INC
SOLEShares541.67K
TypeSH
Market value$7.66M
1.71%
Sole
541.67K
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$6.72M
1.50%
Sole
3.63M
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares572.66K
TypeSH
Market value$6.10M
1.37%
Sole
572.66K
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$6.03M
1.35%
Sole
1.20M
Shared
0.00
None
0.00
MERSANA THERAPEUTICS INC
SOLEShares1.30M
TypeSH
Market value$5.85M
1.31%
Sole
1.30M
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares790.44K
TypeSH
Market value$5.31M
1.19%
Sole
790.44K
Shared
0.00
None
0.00
Q32 BIO INC
SOLEShares251.99K
TypeSH
Market value$4.29M
0.96%
Sole
251.99K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
ENLIVEN THERAPEUTICS INCSOLE | COM | 3.84M | SH | $67.47M 15.11% | 3.84M | 0.00 | 0.00 |
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $62.47M 13.99% | 4.41M | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INCSOLE | COM | 1.24M | SH | $37.26M 8.34% | 1.24M | 0.00 | 0.00 |
MERUS N VSOLE | COM | 548.83K | SH | $24.71M 5.53% | 548.83K | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 497.27K | SH | $20.87M 4.67% | 497.27K | 0.00 | 0.00 |
PRAXIS PRECISION MEDICINES ISOLE | COM NEW | 340K | SH | $20.75M 4.65% | 340K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 237.56K | SH | $19.48M 4.36% | 237.56K | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 797.60K | SH | $18.43M 4.13% | 797.60K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 319.97K | SH | $17.50M 3.92% | 319.97K | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 665.55K | SH | $16.98M 3.80% | 665.55K | 0.00 | 0.00 |
TYRA BIOSCIENCES INCSOLE | COM | 939.30K | SH | $15.40M 3.45% | 939.30K | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $15.08M 3.38% | 6.36M | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 282.31K | SH | $14.18M 3.18% | 282.31K | 0.00 | 0.00 |
CENTESSA PHARMACEUTICALS PLCSOLE | SPONSORED ADS | 1.25M | SH | $14.07M 3.15% | 1.25M | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 736.60K | SH | $12.90M 2.89% | 736.60K | 0.00 | 0.00 |
SILENCE THERAPEUTICS PLCSOLE | ADS | 476.20K | SH | $10.29M 2.30% | 476.20K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $8.06M 1.80% | 357.73K | 0.00 | 0.00 |
ZENTALIS PHARMACEUTICALS INCSOLE | COM | 490K | SH | $7.72M 1.73% | 490K | 0.00 | 0.00 |
ADVERUM BIOTECHNOLOGIES INCSOLE | COM NEW | 541.67K | SH | $7.66M 1.71% | 541.67K | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $6.72M 1.50% | 3.63M | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 572.66K | SH | $6.10M 1.37% | 572.66K | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $6.03M 1.35% | 1.20M | 0.00 | 0.00 |
MERSANA THERAPEUTICS INCSOLE | COM | 1.30M | SH | $5.85M 1.31% | 1.30M | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 790.44K | SH | $5.31M 1.19% | 790.44K | 0.00 | 0.00 |
Q32 BIO INCSOLE | COM | 251.99K | SH | $4.29M 0.96% | 251.99K | 0.00 | 0.00 |
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