Filed: 2/14/2024ACC: 0001104659-24-023676
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 25 equity positions with a total reported market value of $376.98M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
25
Positions
$376.98M
Total AUM (reported)
39.01M
Total Shares
Allocation by class
COM$336.64M89.3%
COM NEW$19.72M5.2%
CLASS A ORD$18.28M4.8%
ORDINARY SHARES$2.35M0.6%
Portfolio Concentration
Top 3$160.32M42.5%
4–10$116.08M30.8%
11–25$100.58M26.7%
Top 3 weight
42.5%
Top 10 weight
73.3%
Voting Authority Distribution
Total shares with voting rights: 39.01M
Sole
Full voting authority
39.01M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole25
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings25
Rows:
ENLIVEN THERAPEUTICS INC
SOLEShares5.16M
TypeSH
Market value$71.43M
18.95%
Sole
5.16M
Shared
0.00
None
0.00
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$66.52M
17.65%
Sole
4.41M
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares797.60K
TypeSH
Market value$22.37M
5.93%
Sole
797.60K
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares497.27K
TypeSH
Market value$19.72M
5.23%
Sole
497.27K
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares302.63K
TypeSH
Market value$18.28M
4.85%
Sole
302.63K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares399.97K
TypeSH
Market value$17.12M
4.54%
Sole
399.97K
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares294.22K
TypeSH
Market value$16.99M
4.51%
Sole
294.22K
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS INC
SOLEShares1.47M
TypeSH
Market value$15.31M
4.06%
Sole
1.47M
Shared
0.00
None
0.00
MERUS N V
SOLEShares521.53K
TypeSH
Market value$14.34M
3.80%
Sole
521.53K
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$14.31M
3.80%
Sole
6.36M
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares586.60K
TypeSH
Market value$12.78M
3.39%
Sole
586.60K
Shared
0.00
None
0.00
MIRATI THERAPEUTICS INC
SOLEShares192.50K
TypeSH
Market value$11.31M
3.00%
Sole
192.50K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares585K
TypeSH
Market value$10.89M
2.89%
Sole
585K
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$8.68M
2.30%
Sole
3.63M
Shared
0.00
None
0.00
TYRA BIOSCIENCES INC
SOLEShares554.98K
TypeSH
Market value$7.69M
2.04%
Sole
554.98K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$7.66M
2.03%
Sole
357.73K
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$7.53M
2.00%
Sole
1.20M
Shared
0.00
None
0.00
ZENTALIS PHARMACEUTICALS INC
SOLEShares490K
TypeSH
Market value$7.42M
1.97%
Sole
490K
Shared
0.00
None
0.00
SPRUCE BIOSCIENCES INC
SOLEShares2.36M
TypeSH
Market value$6.93M
1.84%
Sole
2.36M
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares665.55K
TypeSH
Market value$6.02M
1.60%
Sole
665.55K
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares790.44K
TypeSH
Market value$4.65M
1.23%
Sole
790.44K
Shared
0.00
None
0.00
MERSANA THERAPEUTICS INC
SOLEShares1.30M
TypeSH
Market value$3.03M
0.80%
Sole
1.30M
Shared
0.00
None
0.00
HOMOLOGY MEDICINES INC
SOLEShares4.54M
TypeSH
Market value$2.76M
0.73%
Sole
4.54M
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares404.40K
TypeSH
Market value$2.35M
0.62%
Sole
404.40K
Shared
0.00
None
0.00
CIDARA THERAPEUTICS INC
SOLEShares1.13M
TypeSH
Market value$900.8K
0.24%
Sole
1.13M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
ENLIVEN THERAPEUTICS INCSOLE | COM | 5.16M | SH | $71.43M 18.95% | 5.16M | 0.00 | 0.00 |
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $66.52M 17.65% | 4.41M | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 797.60K | SH | $22.37M 5.93% | 797.60K | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 497.27K | SH | $19.72M 5.23% | 497.27K | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 302.63K | SH | $18.28M 4.85% | 302.63K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 399.97K | SH | $17.12M 4.54% | 399.97K | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 294.22K | SH | $16.99M 4.51% | 294.22K | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INCSOLE | COM | 1.47M | SH | $15.31M 4.06% | 1.47M | 0.00 | 0.00 |
MERUS N VSOLE | COM | 521.53K | SH | $14.34M 3.80% | 521.53K | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $14.31M 3.80% | 6.36M | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 586.60K | SH | $12.78M 3.39% | 586.60K | 0.00 | 0.00 |
MIRATI THERAPEUTICS INCSOLE | COM | 192.50K | SH | $11.31M 3.00% | 192.50K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 585K | SH | $10.89M 2.89% | 585K | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $8.68M 2.30% | 3.63M | 0.00 | 0.00 |
TYRA BIOSCIENCES INCSOLE | COM | 554.98K | SH | $7.69M 2.04% | 554.98K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $7.66M 2.03% | 357.73K | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $7.53M 2.00% | 1.20M | 0.00 | 0.00 |
ZENTALIS PHARMACEUTICALS INCSOLE | COM | 490K | SH | $7.42M 1.97% | 490K | 0.00 | 0.00 |
SPRUCE BIOSCIENCES INCSOLE | COM | 2.36M | SH | $6.93M 1.84% | 2.36M | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 665.55K | SH | $6.02M 1.60% | 665.55K | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 790.44K | SH | $4.65M 1.23% | 790.44K | 0.00 | 0.00 |
MERSANA THERAPEUTICS INCSOLE | COM | 1.30M | SH | $3.03M 0.80% | 1.30M | 0.00 | 0.00 |
HOMOLOGY MEDICINES INCSOLE | COM | 4.54M | SH | $2.76M 0.73% | 4.54M | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 404.40K | SH | $2.35M 0.62% | 404.40K | 0.00 | 0.00 |
CIDARA THERAPEUTICS INCSOLE | COM | 1.13M | SH | $900.8K 0.24% | 1.13M | 0.00 | 0.00 |