Filed: 11/14/2023ACC: 0001104659-23-118105
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 26 equity positions with a total reported market value of $347.54M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
26
Positions
$347.54M
Total AUM (reported)
41.20M
Total Shares
Allocation by class
COM$317.08M91.2%
CLASS A ORD$17.85M5.1%
COM NEW$8.54M2.5%
ORDINARY SHARES$4.06M1.2%
Portfolio Concentration
Top 3$160.75M46.3%
4–10$99.54M28.6%
11–25$86.18M24.8%
Rest$1.07M0.3%
Top 3 weight
46.3%
Top 10 weight
74.9%
Voting Authority Distribution
Total shares with voting rights: 41.20M
Sole
Full voting authority
41.20M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole26
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings26
Rows:
ENLIVEN THERAPEUTICS INC
SOLEShares5.16M
TypeSH
Market value$70.50M
20.29%
Sole
5.16M
Shared
0.00
None
0.00
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$69.65M
20.04%
Sole
4.41M
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares438.44K
TypeSH
Market value$20.60M
5.93%
Sole
438.44K
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS INC
SOLEShares1.47M
TypeSH
Market value$20.13M
5.79%
Sole
1.47M
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares313.21K
TypeSH
Market value$17.85M
5.14%
Sole
313.21K
Shared
0.00
None
0.00
CRINETICS PHARMACEUTICALS IN
SOLEShares462.29K
TypeSH
Market value$13.75M
3.96%
Sole
462.29K
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$13.49M
3.88%
Sole
6.36M
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares587.60K
TypeSH
Market value$12.26M
3.53%
Sole
587.60K
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$12.24M
3.52%
Sole
3.63M
Shared
0.00
None
0.00
ZENTALIS PHARMACEUTICALS INC
SOLEShares490K
TypeSH
Market value$9.83M
2.83%
Sole
490K
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$8.55M
2.46%
Sole
1.20M
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares310.27K
TypeSH
Market value$8.54M
2.46%
Sole
310.27K
Shared
0.00
None
0.00
MIRATI THERAPEUTICS INC
SOLEShares192.50K
TypeSH
Market value$8.39M
2.41%
Sole
192.50K
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares790.44K
TypeSH
Market value$7.71M
2.22%
Sole
790.44K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares585K
TypeSH
Market value$6.48M
1.86%
Sole
585K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$6.42M
1.85%
Sole
357.73K
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares410K
TypeSH
Market value$6.29M
1.81%
Sole
410K
Shared
0.00
None
0.00
ARVINAS INC
SOLEShares320K
TypeSH
Market value$6.28M
1.81%
Sole
320K
Shared
0.00
None
0.00
TYRA BIOSCIENCES INC
SOLEShares411.45K
TypeSH
Market value$5.67M
1.63%
Sole
411.45K
Shared
0.00
None
0.00
SPRUCE BIOSCIENCES INC
SOLEShares2.36M
TypeSH
Market value$5.34M
1.54%
Sole
2.36M
Shared
0.00
None
0.00
HOMOLOGY MEDICINES INC
SOLEShares4.54M
TypeSH
Market value$5.31M
1.53%
Sole
4.54M
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares665.55K
TypeSH
Market value$4.25M
1.22%
Sole
665.55K
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares404.40K
TypeSH
Market value$4.06M
1.17%
Sole
404.40K
Shared
0.00
None
0.00
MERSANA THERAPEUTICS INC
SOLEShares1.30M
TypeSH
Market value$1.66M
0.48%
Sole
1.30M
Shared
0.00
None
0.00
IMPEL PHARMACEUTICALS INC
SOLEShares2.88M
TypeSH
Market value$1.24M
0.36%
Sole
2.88M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
ENLIVEN THERAPEUTICS INCSOLE | COM | 5.16M | SH | $70.50M 20.29% | 5.16M | 0.00 | 0.00 |
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $69.65M 20.04% | 4.41M | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 438.44K | SH | $20.60M 5.93% | 438.44K | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INCSOLE | COM | 1.47M | SH | $20.13M 5.79% | 1.47M | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 313.21K | SH | $17.85M 5.14% | 313.21K | 0.00 | 0.00 |
CRINETICS PHARMACEUTICALS INSOLE | COM | 462.29K | SH | $13.75M 3.96% | 462.29K | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $13.49M 3.88% | 6.36M | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 587.60K | SH | $12.26M 3.53% | 587.60K | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $12.24M 3.52% | 3.63M | 0.00 | 0.00 |
ZENTALIS PHARMACEUTICALS INCSOLE | COM | 490K | SH | $9.83M 2.83% | 490K | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $8.55M 2.46% | 1.20M | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 310.27K | SH | $8.54M 2.46% | 310.27K | 0.00 | 0.00 |
MIRATI THERAPEUTICS INCSOLE | COM | 192.50K | SH | $8.39M 2.41% | 192.50K | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 790.44K | SH | $7.71M 2.22% | 790.44K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 585K | SH | $6.48M 1.86% | 585K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $6.42M 1.85% | 357.73K | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 410K | SH | $6.29M 1.81% | 410K | 0.00 | 0.00 |
ARVINAS INCSOLE | COM | 320K | SH | $6.28M 1.81% | 320K | 0.00 | 0.00 |
TYRA BIOSCIENCES INCSOLE | COM | 411.45K | SH | $5.67M 1.63% | 411.45K | 0.00 | 0.00 |
SPRUCE BIOSCIENCES INCSOLE | COM | 2.36M | SH | $5.34M 1.54% | 2.36M | 0.00 | 0.00 |
HOMOLOGY MEDICINES INCSOLE | COM | 4.54M | SH | $5.31M 1.53% | 4.54M | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 665.55K | SH | $4.25M 1.22% | 665.55K | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 404.40K | SH | $4.06M 1.17% | 404.40K | 0.00 | 0.00 |
MERSANA THERAPEUTICS INCSOLE | COM | 1.30M | SH | $1.66M 0.48% | 1.30M | 0.00 | 0.00 |
IMPEL PHARMACEUTICALS INCSOLE | COM | 2.88M | SH | $1.24M 0.36% | 2.88M | 0.00 | 0.00 |
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