Filed: 8/14/2023ACC: 0001104659-23-091386
📋 What this filing means
5AM VENTURE MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 24 equity positions with a total reported market value of $401.43M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
24
Positions
$401.43M
Total AUM (reported)
40.06M
Total Shares
Allocation by class
COM$370.87M92.4%
CLASS A ORD$18.23M4.5%
COM NEW$10.53M2.6%
ORDINARY SHARES$1.80M0.4%
Portfolio Concentration
Top 3$206.78M51.5%
4–10$110.56M27.5%
11–25$84.09M20.9%
Top 3 weight
51.5%
Top 10 weight
79.1%
Voting Authority Distribution
Total shares with voting rights: 40.06M
Sole
Full voting authority
40.06M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole24
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings24
Rows:
ENLIVEN THERAPEUTICS INC
SOLEShares5.80M
TypeSH
Market value$118.35M
29.48%
Sole
5.80M
Shared
0.00
None
0.00
ENTRADA THERAPEUTICS INC
SOLEShares4.41M
TypeSH
Market value$66.74M
16.63%
Sole
4.41M
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares488.44K
TypeSH
Market value$21.69M
5.40%
Sole
488.44K
Shared
0.00
None
0.00
RALLYBIO CORP
SOLEShares3.63M
TypeSH
Market value$20.55M
5.12%
Sole
3.63M
Shared
0.00
None
0.00
VOR BIOPHARMA INC
SOLEShares6.36M
TypeSH
Market value$19.66M
4.90%
Sole
6.36M
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares357.49K
TypeSH
Market value$18.23M
4.54%
Sole
357.49K
Shared
0.00
None
0.00
CRINETICS PHARMACEUTICALS IN
SOLEShares862.29K
TypeSH
Market value$15.54M
3.87%
Sole
862.29K
Shared
0.00
None
0.00
ZENTALIS PHARMACEUTICALS INC
SOLEShares490K
TypeSH
Market value$13.82M
3.44%
Sole
490K
Shared
0.00
None
0.00
SCPHARMACEUTICALS INC
SOLEShares1.20M
TypeSH
Market value$12.23M
3.05%
Sole
1.20M
Shared
0.00
None
0.00
CELLDEX THERAPEUTICS INC NEW
SOLEShares310.27K
TypeSH
Market value$10.53M
2.62%
Sole
310.27K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares585K
TypeSH
Market value$9.48M
2.36%
Sole
585K
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares790.44K
TypeSH
Market value$9.36M
2.33%
Sole
790.44K
Shared
0.00
None
0.00
PHARVARIS N V
SOLEShares587.60K
TypeSH
Market value$8.90M
2.22%
Sole
587.60K
Shared
0.00
None
0.00
ARVINAS INC
SOLEShares320K
TypeSH
Market value$7.94M
1.98%
Sole
320K
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares665.55K
TypeSH
Market value$7.38M
1.84%
Sole
665.55K
Shared
0.00
None
0.00
ANAPTYSBIO INC
SOLEShares357.73K
TypeSH
Market value$7.28M
1.81%
Sole
357.73K
Shared
0.00
None
0.00
MIRATI THERAPEUTICS INC
SOLEShares192.50K
TypeSH
Market value$6.96M
1.73%
Sole
192.50K
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares280K
TypeSH
Market value$6.66M
1.66%
Sole
280K
Shared
0.00
None
0.00
SPRUCE BIOSCIENCES INC
SOLEShares2.36M
TypeSH
Market value$5.08M
1.27%
Sole
2.36M
Shared
0.00
None
0.00
MERSANA THERAPEUTICS INC
SOLEShares1.30M
TypeSH
Market value$4.29M
1.07%
Sole
1.30M
Shared
0.00
None
0.00
HOMOLOGY MEDICINES INC
SOLEShares4.54M
TypeSH
Market value$4.01M
1.00%
Sole
4.54M
Shared
0.00
None
0.00
IMPEL PHARMACEUTICALS INC
SOLEShares2.88M
TypeSH
Market value$3.66M
0.91%
Sole
2.88M
Shared
0.00
None
0.00
GH RESEARCH PLC
SOLEShares152.02K
TypeSH
Market value$1.80M
0.45%
Sole
152.02K
Shared
0.00
None
0.00
CIDARA THERAPEUTICS INC
SOLEShares1.13M
TypeSH
Market value$1.28M
0.32%
Sole
1.13M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
ENLIVEN THERAPEUTICS INCSOLE | COM | 5.80M | SH | $118.35M 29.48% | 5.80M | 0.00 | 0.00 |
ENTRADA THERAPEUTICS INCSOLE | COM | 4.41M | SH | $66.74M 16.63% | 4.41M | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 488.44K | SH | $21.69M 5.40% | 488.44K | 0.00 | 0.00 |
RALLYBIO CORPSOLE | COM | 3.63M | SH | $20.55M 5.12% | 3.63M | 0.00 | 0.00 |
VOR BIOPHARMA INCSOLE | COM | 6.36M | SH | $19.66M 4.90% | 6.36M | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 357.49K | SH | $18.23M 4.54% | 357.49K | 0.00 | 0.00 |
CRINETICS PHARMACEUTICALS INSOLE | COM | 862.29K | SH | $15.54M 3.87% | 862.29K | 0.00 | 0.00 |
ZENTALIS PHARMACEUTICALS INCSOLE | COM | 490K | SH | $13.82M 3.44% | 490K | 0.00 | 0.00 |
SCPHARMACEUTICALS INCSOLE | COM | 1.20M | SH | $12.23M 3.05% | 1.20M | 0.00 | 0.00 |
CELLDEX THERAPEUTICS INC NEWSOLE | COM NEW | 310.27K | SH | $10.53M 2.62% | 310.27K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 585K | SH | $9.48M 2.36% | 585K | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 790.44K | SH | $9.36M 2.33% | 790.44K | 0.00 | 0.00 |
PHARVARIS N VSOLE | COM | 587.60K | SH | $8.90M 2.22% | 587.60K | 0.00 | 0.00 |
ARVINAS INCSOLE | COM | 320K | SH | $7.94M 1.98% | 320K | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 665.55K | SH | $7.38M 1.84% | 665.55K | 0.00 | 0.00 |
ANAPTYSBIO INCSOLE | COM | 357.73K | SH | $7.28M 1.81% | 357.73K | 0.00 | 0.00 |
MIRATI THERAPEUTICS INCSOLE | COM | 192.50K | SH | $6.96M 1.73% | 192.50K | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 280K | SH | $6.66M 1.66% | 280K | 0.00 | 0.00 |
SPRUCE BIOSCIENCES INCSOLE | COM | 2.36M | SH | $5.08M 1.27% | 2.36M | 0.00 | 0.00 |
MERSANA THERAPEUTICS INCSOLE | COM | 1.30M | SH | $4.29M 1.07% | 1.30M | 0.00 | 0.00 |
HOMOLOGY MEDICINES INCSOLE | COM | 4.54M | SH | $4.01M 1.00% | 4.54M | 0.00 | 0.00 |
IMPEL PHARMACEUTICALS INCSOLE | COM | 2.88M | SH | $3.66M 0.91% | 2.88M | 0.00 | 0.00 |
GH RESEARCH PLCSOLE | ORDINARY SHARES | 152.02K | SH | $1.80M 0.45% | 152.02K | 0.00 | 0.00 |
CIDARA THERAPEUTICS INCSOLE | COM | 1.13M | SH | $1.28M 0.32% | 1.13M | 0.00 | 0.00 |